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A Randomized, Double-Blind, Placebo-Controlled Phase II Study of Vandetanib Plus Docetaxel/Prednisolone in Patients with Hormone-Refractory Prostate Cancer
(MARY ANN LIEBERT INC, 2009)
Vandetanib (ZACTIMA(TM)) is a once-daily oral anticancer drug that selectively inhibits vascular endothelial growth factor receptor, epidermal growth factor receptor, and rearranged during transfection signaling. This ...
Deleterious effects of VEGFR2 and RET inhibition in a preclinical model of Parkinson’s disease
(Humana Press Inc., 2018)
High-altitude cognitive impairment is prevented by enriched environment including exercise via VEGF signaling
(Frontiers Media, 2019)
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive impairment, mostly attributed to changes in brain perfusion and consequently neuronal death. Enriched environment and voluntary exercise ...
Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents
(Public Library of Science, 2018)