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QSAR analysis of nicotinamidic compounds and design of potential Bruton’s tyrosine kinase (Btk) inhibitors
(Taylor and Francis Online, 2018)
Structural and electronic properties of tyrosine kinases inhibitors
(C M B Association, 2003-09)
Protein tyrosine kinases (TKs) regulate cell proliferation, cell differentiation, and play a fundamental role in signal transduction pathway. Uncontrolled signaling from receptor tyrosine kinases and intracellular tyrosine ...
The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm
(Company of Biologists, 2016-07)
Sperm capacitation is required for fertilization. At the molecular level, this process is associated with fast activation of protein kinase A. Downstream of this event, capacitating conditions lead to an increase in tyrosine ...
Copolymers of glutamic acid and tyrosine are potent inhibitors of oocyte casein kinase II
(1990)
Polypeptides rich in glutamic acid are strong inhibitors purified from isolated nuclei of Xenopus laevis oocytes of casein kinase II. The presence of tyrosine in these peptides greatly enhances their inhibitory capacity. ...
Direct inhibition of the hexose transporter glut1 by tyrosine kinase inhibitors
(AMERICAN CHEMICAL SOCIETY, 2001)
New mutation L324M in the ABL1 kinase domain: does it confer high resistance to second-generation inhibitors?
(Taylor & Francis Ltd, 2014-03)
In chronic myeloid leukemia (CML) the presence of mutations in the tyrosine kinase domain (TK) of the normalABL1 gene is the most common cause of loss of response to treatment. Detection of these mutations is an important ...