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A comprehensive characterization of cell cultures and xenografts derived from a human verrucous penile carcinoma
(2016-08-01)
This study aimed to establish and characterize primary cell cultures and xenografts derived from penile carcinoma (PeCa) in order to provide experimental models for cellular processes and efficacy of new treatments. A ...
Combined Microdialysis-Tumor Homogenate Method for the Study of the Steady State Compartmental Distribution of a Hydrophobic Anticancer Drug in Patient-Derived Xenografts
(Springer, 2014-03)
PURPOSE: To develop a reproducible microdialysis-tumor homogenate method for the study of the intratumor distribution of a highly hydrophobic anticancer drug (SN-38; 7-ethyl-10-hydroxycamptothecin) in neuroblastoma ...
The growth of glioblastoma orthotopic xenografts in nude mice is directly correlated with impaired object recognition memory
(Elsevier ScienceNew York, 2014-01-17)
Cognitive dysfunction is found in patients with brain tumors and there is a need to determine whether it can be replicated in an experimental model. In the present study, the object recognition (OR) paradigm was used to ...
Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors
(2013-04-01)
Breast cancer is the most common type of cancer among women worldwide. Research using breast cancer cell lines derived from primary tumors may provide valuable additional knowledge regarding this type of cancer. Therefore, ...
Genomic and phenotypic profiles of two Brazilian breast cancer cell lines derived from primary human tumors
(2013-04-01)
Breast cancer is the most common type of cancer among women worldwide. Research using breast cancer cell lines derived from primary tumors may provide valuable additional knowledge regarding this type of cancer. Therefore, ...
Preclinical platform of retinoblastoma xenografts recapitulating human disease and molecular markers of dissemination
(Elsevier Ireland, 2016-09)
Translational research in retinoblastoma – a pediatric tumor that originates during the development of the retina – would be improved by the creation of new patient-derived models. Using tumor samples from enucleated eyes ...