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FMNL1 promotes proliferation and migration of leukemia cells
(Federation Amer Soc Exp BiolBethesdaEUA, 2013)
TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response
(Rockefeller University Press, 2015-09)
Leukocyte transendothelial migration (TEM) is a tightly regulated, multistep process that is critical to the inflammatory response. A transient increase in endothelial cytosolic free calcium ion concentration (↑[Ca2+]i) ...
O efeito da desintegrina DisBa-01 e do silenciamento da integrina avB3 e na interação de células tumorais e endoteliais in vitro
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, 2013-02-27)
Metastasis depends on several physiological processes such as cell adhesion, transendothelial cell migration and proliferation. These events are mediated mostly by integrins, which are adhesion receptors present on cell ...
Thy-1 (CD90)-induced metastatic cancer cell migration and invasion are β3 integrin-dependent and involve a Ca2+/P2X7 receptor signaling axis
(Frontiers Media, 2021)
Cancer cell adhesion to the vascular endothelium is an important step in tumor
metastasis. Thy-1 (CD90), a cell adhesion molecule expressed in activated endothelial
cells, has been implicated in melanoma metastasis by ...
The effect of DMSA-functionalized magnetic nanoparticles on transendothelial migration of monocytes in the murine lung via a beta(2) integrin-dependent pathway
(ELSEVIER SCI LTD, 2010)
Magnetic nanoparticles surface-functionalized with meso-2,3-dimercaptosuccinic acid (MNPs-DMSA) constitute an innovative and promising approach for tissue- and cell-targeted delivery of therapeutic drugs in the lung. ...
Estudo do papel da ADAM9 na disseminação tumoral via sistema linfático: possível alvo farmacológico
(Universidade Federal de São CarlosBRUFSCarPrograma Interinstitucional de Pós-Graduação em Ciências Fisiológicas - PIPGCF, 2014-12-12)
Tumor spreading occurs mainly by two pathways: through blood vessels and by lymphatic vessels, but the last is preferred by breast tumor cells. Some proteins are involved in cell adhesion and proteolysis, causing metastasis, ...
Multivectorial Abnormal Cell Migration in the NOD Mouse Thymus
(American Association of Immunologists, 2018)
Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma metastasis
(2018)
Aim: To track early events during lung metastasis, we labeled cells expressing (B16F10(CAV1)) or lacking CAV1 (B16F10(mock)) with gold nanoparticles conjugated to the peptide TAT (AuNPs-PEG-TAT). Methods: B16F10 expressing ...
Gold nanoparticles as tracking devices to shed light on the role of caveolin-1 in early stages of melanoma metastasis
(2018)
Aim: To track early events during lung metastasis, we labeled cells expressing (B16F10(CAV1)) or lacking CAV1 (B16F10(mock)) with gold nanoparticles conjugated to the peptide TAT (AuNPs-PEG-TAT). Methods: B16F10 expressing ...