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Therapeutic targets in chagas disease
(2017-01-01)
Optimal pharmacotherapy occurs when we have selectivity and no toxicity. The discovery of specific pathways or enzymes that are vital forcell or parasite survival is also vital for the design of new specific, non-toxic ...
Current drug nano-targeting strategies for improvement in the diagnosis and treatment of prevalent pathologies such as cardiovascular and renal diseases
(Bentham Science Publishers, 2019-08)
Background: The kidney and cardiovascular system are closely related to each other during the modulation of the cardiovascular homeostasis. However, the search for new alternatives for the treatment and diagnosis of ...
Frequency of self-monitoring blood glucose and attainment of HbA1c target values
(Springer, 2015-04)
Aims: Test strips for self-monitoring of blood glucose (SMBG) represent in Argentina, around 50 % of diabetes treatment cost; the frequency of their use is closely associated with hyperglycemia treatment. However, the ...
Nanosystem functionalization strategies for prostate cancer treatment: a review
(2021-01-01)
Prostate cancer (PC) has a high morbidity and mortality rate worldwide, and the current clinical guidelines can vary depending on the stage of the disease. Drug delivery nanosystems (DDNs) can improve biopharmaceutical ...
Nanotechnology-based drug delivery systems for treatment of oral cancer: a review
(Dove Medical Press Ltd, 2014-01-01)
Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, ...
Highlights in targeted nanoparticles as a delivery strategy for glioma treatment
(2021-07-15)
Glioma is the most common type of Central Nervous System (CNS) neoplasia and it arises from glial cells. As glial cells are formed by different types of cells, glioma can be classified according to the cells that originate ...
Clear Shot at Primary Aim: Susceptibility of Trypanosoma cruzi Organelles, Structures and Molecular Targets to Drug Treatment
(Bentham Science Publishers, 2017)
Geographically targeted interventions versus mass drug administration to control Taenia solium cysticercosis, Peru
(Centers for Disease Control and Prevention, 2021)
Optimal control strategies for Taenia solium taeniasis and cysticercosis have not been determined. We conducted a 2-year cluster randomized trial in Peru by assigning 23 villages to 1 of 3 geographically targeted intervention ...