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Caracterização de componentes da via TOR (target of rapamycin) em Trypanosoma cruzi
(Fundação Oswaldo Cruz. Instituto Carlos Chagas., 2018)
Bioproperties, Nanostructured System and Analytical and Bioanalytical Methods for Determination of Rapamycin: A Review
(2020-01-01)
The drug rapamycin is a potent inhibitor of the mTOR complex, acting directly in the signaling cascade of this protein complex; interrupting cell proliferation, in addition to being an extremely efficient immunosuppressant. ...
mTOR inhibition impairs extinction memory reconsolidation
(Cold Spring Harbor Laboratory, 2020-12-15)
Targeting autophagy in neurodegenerative diseases
(Elsevier Ltd, 2014)
© 2014 Elsevier B.V. All rights reserved. The most prevalent neurodegenerative disorders involve protein misfolding and the aggregation of specific proteins. Autophagy is becoming an attractive target to treat neurodegenerative ...