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Diffuse systemic sclerosis and autoimmune hepatitis: a unique association
(SPRINGER LONDON LTD, 2010)
Autoimmune hepatitis (AIH) is a chronic hepatitis of unknown etiology characterized by continuing hepatocellular necrosis and inflammation that afflicts 100,000 to 200,000 persons in the United States. It is a rare ...
A new promising treatment in systemic sclerosis: 5-fluorouracil
(BMJ Publishing Group, 1987)
Twelve patients with systemic sclerosis according to American Rheumatism Association criteria were treated with intravenous 5-fluorouracil. Significant subjective and objective improvement occurred initially in the skin ...
Assessment of light touch sensation in the hands of systemic sclerosis patients
(Faculdade de Medicina / USP, 2014-09-01)
INTRODUCTION: Systemic sclerosis is a relatively rare connective tissue disorder characterized by severe and progressive fibrosis of the skin. Due to the current lack of available information on this subject, the aim of ...
Is there a window of opportunity for the therapeutic use of vitamin D in multiple sclerosis?
(2022-09-01)
Multiple sclerosis is an autoimmune treatable but not curable disease. There are a multiplicity of medications for multiple sclerosis therapy, including a class entitled disease-modifying drugs that are mainly indicated ...
Should mast cells be considered therapeutic targets in multiple sclerosis?
(2020-11-01)
Mast cells are immune cells of the myeloid lineage that are found throughout the body, including the central nervous system. They perform many functions associated with innate and specific immunity, angiogenesis, and ...
Systemic sclerosis patients present alterations in the expression of molecules involved in B-cell regulation
(Frontiers Media, 2015)
The activation threshold of B cells is tightly regulated by an array of inhibitory and activator receptors in such a way that disturbances in their expression can lead to the appearance of autoimmunity. The aim of this ...
Ocular findings in patients with systemic sclerosis
(Faculdade de Medicina / USP, 2011)
OBJECTIVE: To evaluate the frequency and characteristics of ocular manifestations in outpatients with systemic sclerosis. METHODS: In this cross-sectional study, 45 patients with systemic sclerosis were enrolled. Data ...
Curcumin as a therapeutic candidate for multiple sclerosis: Molecular mechanisms and targets
(Wiley-Liss Inc., 2019)