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Neurogenic hypertension and the secrets of respiration
(Amer Physiological Soc, 2017-06-01)
Despite recent advances in the knowledge of the neural control of cardiovascular function, the cause of sympathetic overactivity in neurogenic hypertension remains unknown. Studies from our laboratory point out that rats ...
Role of A5 noradrenergic neurons in the chemoreflex control of respiratory and sympathetic activities in unanesthetized conditions
(2017-06-23)
The A5 area at the ventrolateral pons contains noradrenergic neurons connected with other medullary areas involved in the cardiorespiratory control. Its contribution to the cardiorespiratory regulation was previously ...
Electrophysiological properties of rostral ventrolateral medulla presympathetic neurons modulated by the respiratory network in rats
(2013)
The respiratory pattern generator modulates the sympathetic outflow, the strength of which is enhanced by challenges produced by hypoxia. This coupling is due to the respiratory-modulated presympathetic neurons in the ...
The nucleus of the solitary tract and the coordination of respiratory and sympathetic activities
(2014)
It is well known that breathing introduces rhythmical oscillations in the heart rate and arterial pressure levels. Sympathetic oscillations coupled to the respiratory activity have been suggested as an important homeostatic ...
Inhibition of neurons in commissural nucleus of solitary tract reduces sympathetic nerve activity in SHR
(Amer Physiological Soc, 2002-05-01)
Neurons in the commissural nucleus of the solitary tract (commNTS) play an important role in certain cardiovascular responses dependent on sympathetic vasoconstrictor activation, including the arterial chemoreceptor reflex. ...
Coupling of respiratory and sympathetic activities in rats submitted to chronic intermittent hypoxia
(Elsevier B.V., 2014-01-01)
The respiratory modulation of sympathetic activity relies on the balance between excitatory and inhibitory inputs from the brainstem respiratory network to presympathetic neurons of the rostral ventrolateral medulla. This ...
The carotid body detects circulating tumor necrosis factor-alpha to activate a sympathetic anti-inflammatory reflex
(2022-05-01)
Recent evidence has suggested that the carotid bodies might act as immunological sensors, detecting pro-inflammatory mediators and signalling to the central nervous system, which, in turn, orchestrates autonomic responses. ...
Properties of the Ryanodine‐sensitive Release Channels that Underlie Caffeine‐induced Ca2+ Mobilization from Intracellular Stores in Mammalian Sympathetic Neurons
(1995)
The most compelling evidence for a functional role of caffeine‐sensitive intracellular Ca2+ reservoirs in nerve cells derives from experiments on peripheral neurons. However, the properties of their ryanodine receptor ...