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Overexpression of survivin in pediatric Hodgkin lymphoma tumor cells: Characterization of protein expression and splice-variants transcription profile
(Academic Press Inc Elsevier Science, 2019-06)
Survivin is abundantly expressed during fetal development but absent in most differentiated adult tissues; an exception being components of the immune system, such as B and T lymphocytes. Beyond acting as a master regulator ...
Naked DNA immunization as an approach to target the generic tumor antigen survivin induces humoral and cellular immune responses in mice
(Elsevier GmbH, 2006)
Survivin, a 16.5 kDa tumor associated antigen, is the smallest member of the inhibitor of apoptosis family that is abundantly expressed during development but essentially absent in normal adult tissues. Interestingly, ...
Smoking cessation leads to changes in survivin expression in oral mucosa
(2018-03-01)
Background: Survivin is an inhibitor protein of apoptosis and plays a role in oral carcinogenesis mechanism. Methods: The aim of this study was to evaluate the effect of smoking in survivin expression of oral mucosa of ...
Intradermal DNA electroporation induces survivin-specific CTLs, suppresses angiogenesis and confers protection against mouse melanoma
(2010)
Survivin is an intracellular tumor-associated antigen that is broadly expressed in a large variety of tumors and also in tumor associated endothelial cells but mostly absent in differentiated tissues. Naked DNA vaccines ...
The 5’ untranslated region of the anti-apoptotic protein Survivin contains an inhibitory upstream AUG codon
(Elsevier, 2020)
Survivin (BIRC5) is an anti-apoptotic protein that is important in cancer. Mechanisms responsible for controlling Survivin levels in cells include transcriptional regulation and modulation of protein stability via ...
Intradermal DNA electroporation induces survivin-speciWc CTLs, suppresses angiogenesis and confers protection against mouse melanoma
(Springer-Verlag, 2010)
Survivin is an intracellular tumor-associated
antigen that is broadly expressed in a large variety of
tumors and also in tumor associated endothelial cells but
mostly absent in diVerentiated tissues. Naked DNA ...
On the discovery of a potential survivin inhibitor combining computational tools and cytotoxicity studies
(Elsevier, 2019-08-01)
Survivin protein is a metalloprotein member of the inhibitors of apoptosis proteins family, involved in the regulation of programmed cell death. Due to the recent development of antitumor therapies having survivin as ...
Inverse expression of survivin and reprimo correlates with poor patient prognosis in gastric cancer
(Impact Journals LLC, 2018)
© Cerda-Opazo et al. BACKGROUND: The objective of the study was to determine the relationship between Survivin and Reprimo transcript/protein expression levels, and gastric cancer outcome. METHODS: In silico correlations ...
Decreased immunoexpression of survivin could be a potential marker in human non-alcoholic fatty liver disease progression?
(WILEY-BLACKWELL PUBLISHING, INC, 2011)
Background/aim Regulation of apoptosis in non-alcoholic fatty liver disease (NAFLD) has been a theme of growing debate. Although no other study assessed the role of survivin in NAFLD, its expression has been reported in ...