Painful experience is a complex entity made up of sensory, affective, motivational and cognitive dimensions. the neural mechanisms involved in pain perception acts in a serial and a parallel way, discriminating and locating ...

The role of endogenous opioid systems in the analgesic response to exogenous opiates remains controversial. We previously reported that mice lacking the peptide neurotransmitter β-endorphin, although unable to produce ...

The mechanisms through which electro-acupuncture (EA) and tricyclic antidepressants produce analgesia seem to be complementary: EA inhibits the transmission of noxious messages by activating supraspinal serotonergic and ...

Inflammation is an immune complex-related tissue damage and / or cell caused by chemical, physical, immunological or microbial. The inflammatory process involves a complex cascade of biochemical and cellular events, including ...

A dor é um dos principais indicadores de enfermidade. Ela é uma sensação desagradável, complexa e extremamente subjetiva, relacionada a algum estímulo lesivo ou potencialmente lesivo ao organismo. Quando esses estímulos ...

El Núcleo accumbens (nAc) es una estructura cerebral clave en el sistema de recompensa. El nAc recibe e integra señalización aferente principalmente excitatoria originada desde diversas regiones del cerebro. El control ...