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Insight into nanoparticle cellular uptake and intracellular targeting
(2014)
Collaborative efforts from the fields of biology, materials science, and engineering are leading to exciting progress in the development of nanomedicines. Since the targets of many therapeutic agents are localized in ...
Subcellular movement of signaling molecules: how and why?
(Nova Science Publishers, 2006)
The biological function of proteins is determined by their cellular localization and subsequent interactions with other factors within a given subcellular compartment. Therefore, it is critical to understand how proteins ...
The predicted subcellular localisation of the sugarcane proteome
(Csiro PublishingCollingwoodAustralia, 2009)
Relationship between structure and photoactivity of porphyrins derived from protoporphyrin IX
(WORLD SCI PUBL CO INC, 2010)
Protoporphyrin (Pp IX) derivatives were prepared to study the relationship between photosensitizer structure and photoactivity, with an emphasis on understanding the role of membrane interactions in the efficiency of ...
Surviving nebulization-induced stress: dexamethasone in pH-sensitive archaeosomes
(Future Medicine, 2016-08)
Aim: To increase the subcellular delivery of dexamethasone phosphate (DP) and stability to nebulization stress, pH-sensitive nanoliposomes (LpH) exhibiting archaeolipids, acting as ligands for scavenger receptors (pH-sensitive ...
mCherry fusions enable the subcellular localization of periplasmic and cytoplasmic proteins in Xanthomonas sp.
(2020-07-01)
Fluorescent markers are a powerful tool and have been widely applied in biology for different purposes. The genome sequence of Xanthomonas citri subsp. citri (X. citri) revealed that approximately 30% of the genes encoded ...
Single-Fluorophore Indicator to Explore Cellular and Sub-cellular Lactate Dynamics
(2022-11-25)
Lactate is an energy substrate and an intercellular signal, which can be monitored in intact cells with the genetically encoded FRET indicator Laconic. However, the structural complexity, need for sophisticated equipment, ...
Validating subcellular localization prediction tools with mycobacterial proteins
(2009)
Background: The computational prediction of mycobacterial proteins' subcellular localization is of key importance for proteome annotation and for the identification of new drug targets and vaccine candidates. Several ...