By placing stiff structures under soft materials, prior studies have demonstrated that cells sense and prefer to position themselves over the stiff structures. However, an understanding of how cells migrate on such surfaces ...

In the 1960 s, the first studies of diastolic function appeared and from there the interest in this phase of the cardiac cycle increased. Such interest has continued to the present day, when systole and diastole are equally ...

Natural (or biological) materials usually achieve outstanding mechanical performances. In particular, cancellous bone presents a high stiffness/strength to weight ratio, so its structure inspires the development of novel ...

By means of continuous topology optimization, this paper discusses the influence of material gradation and layout in the overall stiffness behavior of functionally graded structures. The formulation is associated to symmetry ...

A biological process of bone remodeling happens everyday naturally like an optimization process. Hybrid cellular automaton algorithm was developed to simulate this adaptative functional process at tissue level. In the ...

El estudio de biomateriales metálicos aplicados a la ingeniería de tejidos, como las estructuras de sustento celular, ha tomado gran relevancia y se ha dirigido a mejorar el control de las propiedades físicas, mecánicas y ...

The internal structures of the antlers of deer and elk have the characteristic of being cellular structures, which are constituted by a thin region of solid bone in the outer zone of the antlers, and a porous region ...

This paper presents a method to analyze elastic deformations and stiffness in two-dimensional structures with different assembly configurations among their elements. Initially, the optimal structure is obtained through ...