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κ Opioid receptor-mediated depression of activity evoked in convergent dorsal horn cells by thermal and non-thermal noxious stimulation
(1990)
The response of convergent dorsal horn cells to tonic and phasic noxiuos heating and to noxious pinching was studied and after topical application of a solution (30 nmol) of the κ agonist U-50,488H to the dorsal surface ...
Immunohistochemical Protocol To Identify Glial Fibrillary Acid Protein (gfap) In The Dorsal Horn Of The Spinal Cord
(FEDERATION AMER SOC EXP BIOLBETHESDA, 2015)
Expression of nitric oxide synthase isoforms in the dorsal horn of monoarthritic rats: effects of competitive and uncompetitive N-methyl-D-aspartate antagonists
(2007)
Chronic pain is associated with N-methyl-D-aspartate (NMDA) receptor activation and downstream production of nitric oxide, which has a pivotal role in multisynaptic local circuit nociceptive processing in the spinal cord. ...
Centralization of noxious stimulus-induced analgesia (NSIA) is related to activity at inhibitory synapses in the spinal cord
(Elsevier Science BvAmsterdamHolanda, 2009)
Sodium-calcium exchanger-3 regulates pain "wind-up": From human psychophysics to spinal mechanisms
(Elsevier, 2022)
Repeated application of noxious stimuli leads to a progressively increased pain perception; this temporal summation is enhanced in and predictive of clinical pain disorders. Its electrophysiological correlate is “wind-up,” ...
Differential expression of microRNAs in mouse pain models
(BIOMED CENTRAL LTD, 2011)
Background: MicroRNAs (miRNAs) are short non-coding RNAs that inhibit translation of target genes by binding to their mRNAs. The expression of numerous brain-specific miRNAs with a high degree of temporal and spatial ...