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The tyrosine kinase inhibitor nilotinib is more efficient than mitotane in decreasing cell viability in spheroids prepared from adrenocortical carcinoma cells
(BioMed Central, 2018)
Abstract
Background
New drugs for adrenocortical carcinoma (ACC) are needed because most patients undergo rapid disease progression despite surgery and adjuvant therapy ...
Axonal swellings and spheroids: a new insight into the pathology of neurocysticercosis
(Wiley, 2018)
Neurocysticercosis is a parasitic brain disease caused by the larval form (Cysticercus cellulosae) of the Taenia solium and is the leading cause of preventable epilepsy world-wide. However, the pathophysiology and relation ...
Multicellular spheroid formation and evolutionary conserved behaviors of apple snail hemocytes in culture
(Elsevier, 2013-03)
A hemocyte primary culture system for Pomacea canaliculata in a medium mimicking hemolymphatic plasma composition was developed. Hemocytes adhered and spread onto culture dish in the first few hours after seeding but ...
3D spheroid cell cultures and their role in bone regeneration: a systematic review
(Facultad de Odontología. Universidad de Costa Rica, 2022)
Historical evolution of spheroids and organoids, and possibilities of use in life sciences and medicine
(2021-05-01)
Background: An impressive percentage of biomedical advances were achieved through animal research and cell culture investigations. For drug testing and disease researches, both animal models and preclinical trials with ...
Suicide gene therapy on spontaneous canine melanoma: correlations between in vivo tumors and their derived multicell spheroids in vitro
(Nature Publishing Group, 2010-01)
To validate the use of multicellular spheroids to predict the efficacy of herpes simplex thymidine kinase/ganciclovir (HSVtk/GCV) suicide gene therapy in the respective in vivo tumors, we established and characterized 15 ...
Exploring different Convolutional Neural Networks architectures to identify cells in spheroids
(Sociedade Brasileira de Engenharia Biom??dica, 2020)
Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking
(2018)
Chronic alcohol intake leads to neuroinflammation and astrocyte dysfunction, proposed to perpetuate alcohol consumption and to promote conditioned relapse-like binge drinking. In the present study, human mesenchymal stem ...
A Quantitative Assessment of the Morphological Characteristics of BeWo Cells as an in vitro Model of Human Trophoblast Cells
(Sociedad Chilena de Anatomía, 2010)
Interferon-B lipofection I: Increased efficacy of chemotherapeutic drugs on human tumor cells derived monolayers and spheroids
(Nature Publishing Group, 2012-05)
We evaluated the effect of hIFNΒ gene transfer alone or in combination with different antineoplastic drugs commonly used in cancer treatment. Five human tumor-derived cell lines were cultured as monolayers and spheroids. ...