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El heterocomplejo hsp90-inmunofilina de alto peso molecular como maquinaria molecular de transporte de proteínas solublesThe hsp90•high molecular weight immunophilin heterocomplex as a molecular machinery for soluble protein trafficking
(Universidad de Buenos Aires, 2005-06-28)
Es sabido que el movimiento de proteínas englobadas en vesículas utiliza al citoesqueleto como vías de transporte. Sin embargo, nada se sabe acerca del mecanismo de transporte de proteínas solubles no asociadas a vesículas. ...
Transbilayer asymmetry and sphingomyelin composition modulate the preferential membrane partitioning of the nicotinic acetylcholine receptor in Lo domains
(Elsevier Science Inc, 2015-12)
We have previously shown that the intact nicotinic acetylcholine receptor (AChR) lacks preference for Lo domains when reconstituted in a sphingomyelin (SM), cholesterol (Chol) and POPC (1:1:1) model system (Bermúdez V, ...
Maternal and neonatal circulating visfatin concentrations in patients with pre-eclampsia and a small-for-gestational age neonate
(TAYLOR & FRANCIS LTD, 2010)
Objective. Maternal circulating visfatin concentrations are higher in patients with a small-for-gestational-age (SGA) neonate than in those who delivered an appropriate-for-gestational age (AGA) neonate or in those with ...
STREM-1 based sepsis detection with centrifugal microfluidics incorporating active valves and image analysis
(2017-11-17)
Sepsis is the main cause of neonate death in hospitals. According to WHO, around one million neonatal deaths are caused each year because of sepsis. Rapid and early sepsis detection, are necessary for effective treatment ...
Evaluation of the volumetric mass transfer coefficient as scale up parameter for CHO cell cultures for monoclonal antibodies production
(Universidad Nacional de ColombiaBogotá - Ingeniería - Maestría en Ingeniería - Ingeniería QuímicaDepartamento de Ingeniería Química y AmbientalFacultad de IngenieríaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021-08-20)
Actualmente, los anticuerpos monoclonales (mAbs) corresponden al segmento más importante en el mercado de productos biotecnológicos con efecto terapéutico. La síntesis a escala industrial de este tipo de proteínas recombinantes ...