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A strategy to identify genomic expression at single-cell level or a small number of cells
(Pontificia Universidad Católica de Valparaíso, 2005)
Origins, potency, and heterogeneity of skeletal muscle fibro-adipogenic progenitors—time for new definitions
(2021)
Abstract
Striated muscle is a highly plastic and regenerative organ that regulates body movement, temperature, and metabolism—all the functions needed for an individual’s health and well-being. The muscle ...
One-pot fungal biomass-to-biodiesel process: Influence of the molar ratio and the concentration of acid heterogenous catalyst on reaction yield and costs
(2021-09-15)
This work evaluates a microbial-based biodiesel production process through simultaneous esterification and transesterification of the lipid-rich fungal biomass using ethanol as both extractor and acyl acceptor. Two of the ...
Prediction of cell position using single-cell transcriptomic data: an iterative procedure
(F1000 Research Ltd, 2019-10)
Single-cell sequencing reveals cellular heterogeneity but not cell localization. However, by combining single-cell transcriptomic data with a reference atlas of a small set of genes, it would be possible to predict the ...
Characterization of heterogeneous response to chemotherapy by perturbation-based modeling of fluorescent sphingolipid metabolism in cancer cell subpopulations
(2017)
Cancer treatments options are limited by the generation of therapy resistance, which is due by intratumoral heterogeneity in cell response. The study of resistance requires biosensors able to report the response at the ...
Single cell "glucose nanosensor" verifies elevated glucose levels in individual cancer cells
(ACS Publications, 2019)
Single particle tracking of internalized metallic nanoparticles reveals heterogeneous directed motion after clathrin dependent endocytosis in mouse chromaffin cells
(IOP Publishing, 2018-01)
Most accepted single particle tracking methods are able to obtain high-resolution trajectories for relatively short periods of time. In this work we apply a straightforward combination of single-particle tracking microscopy ...
Probing infectious disease by single-cell RNA sequencing: progresses and perspectives
The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life
science and biomedical research has significantly increased our understanding of the cellular
heterogeneities in immunology, oncology ...
Intratumor heterogeneity index of breast carcinomas based on DNA methylation profiles
(BioMed Central, 2019-04)
Background: Cancer cells evolve and constitute heterogeneous populations that fluctuate in space and time and are subjected to selection generating intratumor heterogeneity. This phenomenon is determined by the acquisition ...