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Silymarin exacerbates p53-mediated tubular apoptosis in glycerol-induced acute kidney injury in rats
(Informa HealthcareLondonInglaterra, 2010)
Effects of oral administration of silymarin in a juvenile murine model of non-alcoholic steatohepatitis
(Molecular Diversity Preservation International, 2017-09)
The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) in adolescents is challenging the global care system. No therapeutic strategies have been defined so far, and changes in the lifestyle remain the only ...
Silimarina modifica a atividade da Na+/K+-ATPase e da MAO e modula a ação de antimicrobianos in vitro
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2015-06-10)
The Silymarin is a flavonolignan complex isolated from milk thistle seeds of Silybum marianum being used in the treatment of injury related to oxidative stress, including liver and neurological diseases, as Parkinson ...
Cellular and molecular effects of silymarin on the transdifferentiation processes of LX-2 cells and its connection with lipid metabolism
(2020-05-01)
Fibrosis process in the liver is a clinical condition established in response to chronic lesions and may be reversible in many situations. In this process, hepatic stellate cells (HSCs) activate and produce extracellular ...
Protective effect of Cassia fistula Linn. on diethylnitrosamine induced hepatocellular damage and oxidative stress in ethanol pretreated rats
(Sociedad de Biología de Chile, 2010)
CONCENTRATIONS OF SILYMARIN ON THE RUMEN ACTIVITIES IN LAMBSCONCENTRATIONS OF SILYMARIN ON THE RUMEN ACTIVITIES IN LAMBS
(Universidade Federal de Mato Grosso, 2023)
Biochemical bases of the pharmacological action of the flavonoid silymarin and of its structural isomer silibinin
(1994)
The flavonoid silymarin and one of its structural components, silibinin, have been well characterized as hepato-protective substances. However, little is known about the biochemical mechanisms of action of these substances. ...
Inhibitory effect of the flavonoid silymarin on the erythrocyte hemolysis induced by phenylhydrazine
(1985)
The flavonoid silymarin, which is used as a therapeutical agent in the treatment of liver diseases, can inhibit the hemolysis and lipid peroxidation induced by phenylhydrazine on erythrocytes obtained from rats treated ...
Efeito da silimarina e silibinina sobre as alterações comportamentais e neuroquímicas induzidas por 6-hidroxidopamina em camundongos
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2018-10-11)
Parkinson's disease (PD) is a disabling neurodegenerative disease that affects about 1-2% of the world's population. L-dopa is the most used treatment to attenuate the symptoms of PD; however, in the long term this drug ...