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Multiple gene knock-down by a single lentiviral vector expressing an array of short hairpin RNAs
(Pontificia Universidad Católica de Valparaíso, 2006)
Inhibition of Expression of HTLV-1 Structural Genes Mediated by Short Hairpin RNA In Vitro
(INT INST ANTICANCER RESEARCH, 2011)
Background: Human T-lymphotropic virus 1 (HTLV-1) is associated with the T-cell malignancy known as adult T-cell leukemia! lymphoma (ATLL) and with a disorder called HTLV-1-associated myelopathy/tropical spastic paraparesis ...
The relation between hairpin formation bymitochondrialWANCY tRNAs and the occurrence of the light strand replication origin in Lepidosauria
(Elsevier, 2014)
Mitochondrial light strand DNA replication is initiated at light strand replication origins (OLs), short stem-loop
hairpins formed by the heavy strand DNA. OL-like secondary structures are also formed by heavy strand ...
The relation between hairpin formation by mitochondrial WANCY tRNAs and the occurrence of the light strand replication origin in Lepidosauria
(Elsevier, 2014)
Mitochondrial light strand DNA replication is initiated at light strand replication origins (OLs), short stem-loop hairpins formed by the heavy strand DNA. OL-like secondary structures are also formed by heavy strand DNA ...
HextractoR: an R package for automatic extraction of hairpins from genome-wide data
(Cold Spring Harbor Laboratory Press, 2020-10)
Extracting stem-loop sequences (hairpins) from genome-wide data is very important nowadays for some data mining tasks in bioinformatics. The genome preprocessing is very important because it has a strong influence on the ...
RNA interference against aldehyde dehydrogenase-2: development oftools for alcohol research
(ELSEVIER, 2009)
Liver alcohol dehydrogenase oxidizes ethanol to acetaldehyde, which is further oxidized to acetate by aldehyde dehydrogenase-2
(ALDH2*1). Individuals who carry a low-activity ALDH2 (ALDH2*2) display high blood acetaldehyde ...
A short hairpin RNA-based adjuvant targeting NF-κB repressor IκBα promotes migration of dermal dendritic cells to draining lymph nodes and antitumor CTL responses induced by DNA vaccination
(Elsevier Ltd, 2017)
© 2017 Elsevier Ltd DNA vaccination is an attractive approach to elicit tumor-specific cytotoxic CD8+ T lymphocytes (CTL), which can mediate protective immunity against tumors. To initiate CTL responses, antigen-encoding ...
Desarrollo de sistema lentiviral para la codificación de un short hairpin RNA que permite el silenciamiento dual de las oncoproteínas E6 y E7 de HPV16 en células de pulmón humano
(Universidad de Chile, 2013)
Introducción: El virus papiloma humano (HPV) es el agente causal del cáncer de cuello
uterino (CCU) y de un subgrupo de tumores de cabeza y cuello, siendo HPV16 el más
prevalente. Este virus de alto riesgo neoplásico ...