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Interaction of shikimic acid with shikimate kinase (Retracted Article. See vol 334, pg 967, 2005)
(Elsevier B.V., 2004-12-03)
The crystal structure of shikimate kinase from Mycobacterium tuberculosis (MtSK) complexed with MgADP and shikimic acid (shikimate) has been determined at 2.3 Angstrom resolution, clearly revealing the amino acid residues ...
Interaction of shikimic acid with shikimate kinase (Retracted Article. See vol 334, pg 967, 2005)
(Elsevier B.V., 2004-12-03)
The crystal structure of shikimate kinase from Mycobacterium tuberculosis (MtSK) complexed with MgADP and shikimic acid (shikimate) has been determined at 2.3 Angstrom resolution, clearly revealing the amino acid residues ...
Shikimate kinase: A potential target for development of novel antitubercular agents
(Bentham Science Publ Ltd, 2007-03-01)
Tuberculosis (TB) remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. However, no new classes of drugs for TB have been developed in the past 30 years. Therefore there is an ...
Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid
(Wiley-Blackwell, 2004-12-01)
Tuberculosis made a resurgence in the mid-1980s and now kills approximately 3 million people a year. The re-emergence of tuberculosis as a public health threat, the high susceptibility of HIV-infected persons and the ...
Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid
(Wiley-Blackwell, 2004-12-01)
Tuberculosis made a resurgence in the mid-1980s and now kills approximately 3 million people a year. The re-emergence of tuberculosis as a public health threat, the high susceptibility of HIV-infected persons and the ...
Effects of the magnesium and chloride ions and shikimate on the structure of shikimate kinase from Mycobacterium tuberculosis
(Blackwell Publishing, 2007-01-01)
Bacteria, fungi and plants can convert carbohydrate and phosphoenolpyruvate into chorismate, which is the precursor of various aromatic compounds. The seven enzymes of the shikimate pathway are responsible for this conversion. ...
Effects of the magnesium and chloride ions and shikimate on the structure of shikimate kinase from Mycobacterium tuberculosis
(Blackwell Publishing, 2007-01-01)
Bacteria, fungi and plants can convert carbohydrate and phosphoenolpyruvate into chorismate, which is the precursor of various aromatic compounds. The seven enzymes of the shikimate pathway are responsible for this conversion. ...
Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: Purification and characterization
(Elsevier B.V., 2006-04-01)
Tuberculosis (TB) poses a major worldwide public health problem. The increasing prevalence of TB, the emergence of multi-drug-resistant strains of Mycobacterium tuberculosis, the causative agent of TB, and the devastating ...
Shikimate kinase: A potential target for development of novel antitubercular agents
(Bentham Science Publ Ltd, 2007-03-01)
Tuberculosis (TB) remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. However, no new classes of drugs for TB have been developed in the past 30 years. Therefore there is an ...
Eichhornia crassipes: an advantageous source of shikimic acid
(Sociedade Brasileira de Farmacognosia, 2014-08-01)
The water hyacinth (Eichhornia crassipes (Mart.) Solms, Pontederiaceae) is considered as one of the most productive plants on earth, and an aquatic weed, which causes serious environmental problems. In this study, this ...