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NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl– concentration
(Wiley Blackwell Publishing, Inc, 2021-08)
The impairment of the cystic fibrosis transmembrane conductance regulator (CFTR) activity induces intracellular chloride (Cl–) accumulation. The anion Cl–, acting as a second messenger, stimulates the secretion of ...
NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl– concentration
(Wiley-Blackwell, 2021)
Abstract:
The impairment of the cystic fibrosis transmembrane conductance regulator (CFTR) activity induces intracellular chloride (Cl–
) accumulation. The anion Cl–
, acting as a second
messenger, stimulates the ...
Uso de peptídeos antimicrobianos contra o câncer: imunomodulação e mecanismos de morte celular
(Universidade Federal de São Paulo (UNIFESP), 2017-05-03)
Cancer is a heterogeneous disease and new therapies are necessaries to evade chemoresistance. Antimicrobial peptides (AMPs) are defense molecules found in different organisms, with antimicrobial activity, and possible ...
Sensitization of U937 leukemia cells to doxorubicin by the MG132 proteasome inhibitor induces an increase in apoptosis by suppressing NF-kappa B and mitochondrial membrane potential loss
(2014)
In this paper, a sensorless control scheme is presented for induction motors with core loss. First, a controller is designed using a high order sliding mode twisting algorithm, to track a desired rotor velocity signal and ...
Estratégias para minimização do estresse oxidativo em sistemas de produção in vitro de embriões bovinos destinados à vitrificação
(Universidade Estadual Paulista (Unesp), 2016-02-03)
O objetivo desse estudo foi avaliar diferentes estratégias para minimizar os efeitos do estresse oxidativo induzido pela menadiona durante o cultivo in vitro sobre o potencial de desenvolvimento embrionário in vitro. Para ...
Efeito farmacogenômico in vitro do Astrocaryum aculeatum em células mononucleares do sangue periférico e de câncer de mama
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2014-01-21)
Breast cancer, due to their prevalence in our environment and global public health is a disease subject of numerous contemporary studies. Some of these studies suggest that certain genes related to cell cycle and apoptosis ...
Estratégias para minimização do estresse oxidativo em sistemas de produção in vitro de embriões bovinos destinados à vitrificação
(Universidade Estadual Paulista (UNESP), 2016)