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Differential effects of novel wasp toxin on rat hippocampal interneurons
(Elsevier B.V., 2002-08-02)
We studied the effects of a wasp toxin beta-pompilidotoxin (beta-PMTX) on rat hippocampal CA1 interneurons by the current-clamp technique. The firing patterns of pyramidal neurons and pyramidale interneurons were not ...
Differential effects of novel wasp toxin on rat hippocampal interneurons
(Elsevier B.V., 2002-08-02)
We studied the effects of a wasp toxin beta-pompilidotoxin (beta-PMTX) on rat hippocampal CA1 interneurons by the current-clamp technique. The firing patterns of pyramidal neurons and pyramidale interneurons were not ...
Differential effects of novel wasp toxin on rat hippocampal interneurons
(Elsevier B.V., 2014)
Characterization of selectivity and pharmacophores of type 1 sea anemone toxins by screening seven Na-v sodium channel isoforms
(ELSEVIER SCIENCE INCNEW YORK, 2013-08-02)
During their evolution, animals have developed a set of cysteine-rich peptides capable of binding various extracellular sites of voltage-gated sodium channels (VGSC). Sea anemone toxins that target VGSCs delay their ...
Transcriptomic analysis of four cerianthid (Cnidaria, Ceriantharia) venoms
(2020-01-01)
Tube anemones, or cerianthids, are a phylogenetically informative group of cnidarians with complex life histories, including a pelagic larval stage and tube-dwelling adult stage, both known to utilize venom in stinging-cell ...
Peptide fingerprinting of the neurotoxic fractions isolated from the secretions of sea anemones Stichodactyla helianthus and Bunodosoma granulifera. New members of the APETx-like family identified by a 454 pyrosequencing approach
(ELSEVIER SCIENCE INCNEW YORK, 2013-08-02)
Sea anemones are known to contain a wide diversity of biologically active peptides, mostly unexplored according to recent peptidomic and transcriptomic studies. In the present work, the neurotoxic fractions from the exudates ...
Validation of a mutant of the pore-forming toxin sticholysin-I for the construction of proteinase-activated immunotoxins
(Oxford University Press, 2011-06-01)
The use of pore-forming toxins from sea anemones (actinoporins) in the construction of immunotoxins (ITs) against tumour cells is an alternative for cancer therapy. However, the main disadvantage of actinoporin-based ITs ...
Validation of a mutant of the pore-forming toxin sticholysin-I for the construction of proteinase-activated immunotoxins
(Oxford University Press, 2011-06-01)
The use of pore-forming toxins from sea anemones (actinoporins) in the construction of immunotoxins (ITs) against tumour cells is an alternative for cancer therapy. However, the main disadvantage of actinoporin-based ITs ...
Validation of a mutant of the pore-forming toxin sticholysin-I for the construction of proteinase-activated immunotoxins
(Oxford University Press, 2014)
Proteomics of the neurotoxic fraction from the sea anemone Bunodosoma cangicum venom: Novel peptides belonging to new classes of toxins
(ELSEVIER SCIENCE INC, 2008)
In contrast to the many studies on the venoms of scorpions, spiders, snakes and cone snails, tip to now there has been no report of the proteomic analysis of sea anemones venoms. In this work we report for the first time ...