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In Vitro Inhibition of Zika Virus Replication with Amantadine and Rimantadine Hydrochlorides
(2021-09-15)
Zika virus (ZIKV) is a mosquito-borne flavivirus in which human infection became relevant
during recent outbreaks in Latin America due to its unrecognized association with fetal neurological
disorders. Currently, there ...
Repurposing potential of rimantadine hydrochloride and development of a promising platinum(II)-rimantadine metallodrug for the treatment of Chikungunya virus infection
(2022-03-01)
Most of the patients infected with Chikungunya virus (CHIKV) develop chronic manifestations characterized by pain and deformity in joints, impacting their quality of life. The aminoadamantanes, in their turn, have been ...
Chemical, spectroscopic characterization, DFT studies and antibacterial activities in vitro of a new gold(I) complex with rimantadine
(Pergamon-elsevier Science LtdOxfordInglaterra, 2012)
Síntesis de nuevos análogos de amantadina, rimantadina y olsetamivir como posibles profármacos con actividad antiviral
(Universidad Autónoma Metropolitana (México). Unidad Azcapotzalco. División de Ciencias Básicas e Ingeniería., 2022)
En el presente trabajo se reporta la síntesis, análisis y caracterización de moléculas análogas de amantadina, rimantadina y olsetamivir, como resultado de la búsqueda y desarrollo de nuevas moléculas con actividad antiviral ...
Structural, Electronic, and Vibrational Properties of Amino-adamantane and Rimantadine Isomers
(AMER CHEMICAL SOC, 2010)
We performed a first principles total energy investigation on the structural, electronic, and vibrational propel ties of adamantane molecules, functionalized with amine and ethanamine groups. We computed the vibrational ...
Un nuevo virus A/H1N1, una nueva pandemia: Influenza un riesgo permanente para una humanidad globalizada
(Colegio Médico del Perú, 2014-07-16)
Influenza is a highly contagious disease. There are some historical descriptions of this condition by ancient Greek physicians, and the etiological agents have been known only for the last eight decades. The causative agent ...
Influenza
(Sociedade Brasileira de Medicina Tropical - SBMT, 2003-04-01)
Influenza (flu) is an acute contagious viral infection characterized by inflammation of the respiratory tract that every winter affects more than 100 million people in Europe, Japan and the United States of America, also ...
Estudio del efecto del sustituyente en el borde inferior de resorcinarenos sulfometilados y su comportamiento en la interacción huésped-hospedero con colina
(Universidad Nacional de ColombiaBogotá - Ciencias - Maestría en Ciencias - QuímicaDepartamento de QuímicaFacultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021)
Este trabajo de investigación tiene como objetivo la síntesis, derivación y caracterización de resorcinarenos corona solubles en agua para evaluar la interacción molecular con colina. En este sentido se llevó a cabo la ...