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Computer-aided design of a novel ligand for retinoic acid receptor in cancer chemotherapy
(Wiley-Blackwell, 2005-05-05)
The isotypes of RAR and RXR are retinoic acid and retinoid X acid receptors, respectively, whose ligand-binding domain contains the ligand-dependent activation function, with distinct pharmacological targets for retinoids, ...
Computer-aided design of a novel ligand for retinoic acid receptor in cancer chemotherapy
(Wiley-Blackwell, 2005-05-05)
The isotypes of RAR and RXR are retinoic acid and retinoid X acid receptors, respectively, whose ligand-binding domain contains the ligand-dependent activation function, with distinct pharmacological targets for retinoids, ...
Computer-aided design of a novel ligand for retinoic acid receptor in cancer chemotherapy
(Wiley-Blackwell, 2014)
Retinoic acid reduces migration of human breast cancer cells: role of retinoic acid receptor beta
(Wiley, 2014-01)
Breast cancer is the most common malignancy in women and the appearance of distant metastases produces the death in 98% of cases. The retinoic acid receptor b (RARb) is not expressed in 50% of invasive breast carcinoma ...
Chronic Ethanol Consumption Alters All-Trans-Retinoic Acid Concentration and Expression of Their Receptors on the Prostate: A Possible Link Between Alcoholism and Prostate Damage
(2013-01-01)
Background: Ethanol (EtOH) alters the all-trans-retinoic acid (ATRA) levels in some tissues. Retinol and ATRA are essential for cell proliferation, differentiation, and maintenance of prostate homeostasis. It has been ...
Chronic Ethanol Consumption Alters All-Trans-Retinoic Acid Concentration and Expression of Their Receptors on the Prostate: A Possible Link Between Alcoholism and Prostate Damage
(2013-01-01)
Background: Ethanol (EtOH) alters the all-trans-retinoic acid (ATRA) levels in some tissues. Retinol and ATRA are essential for cell proliferation, differentiation, and maintenance of prostate homeostasis. It has been ...
Adiponectin, Retinoic Acid Receptor Responder 2, and Peroxisome Proliferator-Activated Receptor-γ Coativator-1 Genes and the Risk for Obesity
(Hindawi Publishing Corporation, 2018)
Graves’ ophthalmopathy: Low-dose dexamethasone reduces retinoic acid receptor-alpha gene expression in orbital fibroblasts
(2018-06-01)
Objective: Graves’ ophthalmopathy (GO) is an autoimmune disease that leads to ocular proptosis caused by fat accumulation and inflammation, and the main treatment is corticosteroid therapy. Retinoid acid receptor-alpha ...
Posteriorization by FGF, Wnt, and retinoic acid is required for neural crest induction
(Academic Press Inc., 2002)
The neural crest is a unique cell population induced at the lateral border of the neural plate. Neural crest is not produced at the anterior border of the neural plate, which is fated to become forebrain. Here, the roles ...