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Mostrando ítems 1-10 de 29
Construcción y evaluación de virus MVA recombinantes que expresan la glicoproteína D del virus BoHV-1Development and evaluation of recombinant MVA viruses expressing bohv-1 glycoprotein D
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2010)
Modified vaccinia virus Ankara as vaccine vectors in human and veterinary medicine
(Future Medicine Ltd, 2015)
Construção de um vírus Vaccínia Ankara Modificado (MVA) Recombinante expressando a proteína e do vírus Dengue 3
(Universidade Federal de Minas GeraisUFMG, 2009-02-27)
Dengue is now the subject of the largest public health campaign in Brazil and is present in 27 states of the Federation. However, because the campaigns to combat the vector have been historically unsuccessful, the development ...
Designing recombinant MVAs as dual-antigen vector vaccines against SARS-CoV-2
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2021)
Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV
(Elsevier, 2017-01)
Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant ...
Construção e avaliação do potencial protetor, em modelo murino, de diferentes construções do Vaccinia Virus Ankara Modificado (MVA) expressando a proteína E de Dengue Virus sorotipos 1, 2 e 4.
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em MicrobiologiaUFMG, 2019-09-30)
Dengue is the main arbovirus that affecting humans and a serious public health
problem. The four dengue virus serotypes (DENV1, 2, 3 and 4) are transmitted
through the bite of female Aedes mosquitoes. A vaccine available ...
Construção, avaliação da imunogenicidade e potencial protetor em modelo murino, de diferentes construções do Vaccinia virus Ankara modificado (MVA) expressando a proteína E de Dengue virus sorotipo 3
(Universidade Federal de Minas GeraisUFMG, 2014-02-20)
Dengue is, currently, the most important human disease caused by an arbovirus. Dengue virus (DENV) has four serotypes (DENV 1-4) and is estimated to be responsible for 390 million infections per year worldwide, in which ...
Caracterização da resposta imune induzida pelo vírus Vaccinia Ankara modificado (MVA) em modelo murino
(Universidade Federal de Minas GeraisUFMG, 2011-03-01)
Since 1796, when the British physician Edward Jenner introduced the concept of vaccination, it became the most important intervention strategy developed to prevent the onset of infectious diseases. Nevertheless, none of ...
Indução do estresse do retículo endoplasmático celular pelo Vaccinia virus: modulação da via UPR durante a infecção viral
(Universidade Federal de Minas GeraisUFMG, 2013-10-30)
The unfolded protein response (UPR) is a cellular response to accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER), induced by a variety of external and internal stimuli, including accumulation ...
MVAΔ008 viral vector encoding the model protein OVA induces improved immune response against the heterologous antigen and equal levels of protection in a mice tumor model than the conventional MVA
(Elsevier, 2021-11)
Modified vaccinia Ankara virus (MVA) is extensively used as a vaccine vector. We have previously observed that MVAΔ008, an MVA lacking the gene that codes for interleukin-18 binding protein, significantly increases CD8+ ...