Background: The addition of adjuvant chemotherapy (ACT) to the surgical treatment of locally advanced colon cancer (CC) was shown to reduce relapses in stage III disease, although it remains controversial in stage II. ...

Botanical drugs are plant-derived, complex mixtures which may have synergistic effects. In order to understand this disparity between human use and drugs approved by regulatory agencies, we analyzed botanical drug clinical ...

The urgency to develop vaccines against Covid-19 is putting pressure on the long and expensive development timelines that are normally required for development of lifesaving vaccines. There is a unique opportunity to ...

We evaluated the secular trend of glycaemic control in individuals with type 2 diabetes in developing countries, where data are limited. Erratum in Correction to: Persistent poor glycaemic control in individuals with type ...

Unfortunately, the standard deviations for ‘last HbA1c measurement’ in mmol/mol were miscalculated in Table 1 of this paper. Erratum for: Persistent poor glycaemic control in individuals with type 2 diabetes in developing ...

OBJECTIVE: We refer to the effectiveness (known as pragmatic or real world) and efficacy (known as explanatory or desired or ideal world) of interventions. However, these terms seem to be randomly chosen by investigators ...

Scientific development that has been achieved through decades finds in clinical research a great possibility of translating findings to human health application. Evidence given by clinical trials allows everyone to have ...