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Part-time cancers and role of melatonin in determining their metabolic phenotype
(2021-08-01)
This brief review describes the association of the endogenous pineal melatonin rhythm with the metabolic flux of solid tumors, particularly breast cancer. It also summarizes new information on the potential mechanisms by ...
Melatonin inhibits Warburg-dependent cancer by redirecting glucose oxidation to the mitochondria: a mechanistic hypothesis
(Springer, 2020-01-22)
Melatonin has the ability to intervene in the initiation, progression and metastasis of some experimental cancers. A large variety of potential mechanisms have been advanced to describe the metabolic and molecular events ...
Circadian and non-circadian melatonin: Influence on glucose metabolism in cancer cells
(Rangsit University, 2020-01)
This review considers the role of melatonin as an oncostatic agent and particularly as to how it relates to the mechanisms by which melatonin regulates glucose metabolism in cancer cells. Many tumor cells adopt a means of ...
Increased reliance on carbohydrates for aerobic exercise in highland andean leaf-eared mice, but not in highland lima leaf-eared mice
(MDPI, 2021)
Exercise is an important performance trait in mammals and variation in aerobic capacity and/or substrate allocation during submaximal exercise may be important for survival at high altitude. Comparisons between lowland and ...
Dichloroacetate and pyruvate metabolism: pyruvate dehydrogenase kinases as targets worth investigating for effective therapy of toxoplasmosis.
(American Society for Microbiology, 2021)
Exercise training enhances rat pancreatic islets anaplerotic enzymes content despite reduced insulin secretion
(SPRINGER, 2011)
Endurance exercise has been shown to reduce pancreatic islets glucose-stimulated insulin secretion (GSIS). Anaplerotic/cataplerotic pathways are directly related to GSIS signaling. However, the effect of endurance training ...