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Directed Differentiation of Neural Progenitors into Neurons Is Accompanied by Altered Expression of P2X Purinergic Receptors
(HUMANA PRESS INC, 2011)
Neural differentiation has been extensively studied in vitro in a model termed neurospheres, which consists of aggregates of neural progenitor cells. Previous studies suggest that they have a great potential for the treatment ...
Pharmacological properties of purinergic receptors and their effects on proliferation and induction of neuronal differentiation of P19 embryonal carcinoma cells
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
We have used P19 embryonal carcinoma cells as in vitro model for early neurogenesis to study ionotropic P2X and metabotropic P2Y receptor-induced Ca2+ transients and their participation in induction of proliferation and ...
Astroglial Ca2+-Dependent Hyperexcitability Requires P2Y1 Purinergic Receptors and Pannexin-1 Channel Activation in a Chronic Model of Epilepsy
(2018)
Astrocytes from the hippocampus of chronic epileptic rats exhibit an abnormal pattern of intracellular calcium oscillations, characterized by an augmented frequency of long lasting spontaneous Ca2C transients, which are ...
Putative roles of purinergic signaling in human immunodeficiency virus-1 infection
(Biomed Central, 2015)
Avaliação do perfil de resposta imune e da expressão dos receptores P2X7, P2Y11 e A2A na forma indeterminada da doença de Chagas
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2016-08-26)
Most infected individuals by protozoan Trypanosoma cruzi is in the indeterminate form of Chagas disease (IFCD), which is characterized by the presence of a tissue inflammatory infiltrate composed by mononuclear cells which ...
Implications of purinergic receptor-mediated intracellular calcium transients in neural differentiation
(Houten, 2013)
Purinergic receptors participate, in almost every cell type, in controlling metabolic activities and many physiological functions including signal transmission, proliferation and differentiation. While most of P2Y receptors ...