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Effects of Ischemic Preconditioning and Postconditioning in a Renal Ischemia-Reperfusion Injury Model: A Comparative Experimental Study in Rats
(Elsevier B.V., 2018-12-01)
Background. Ischemia-reperfusion injury is an unavoidable aspect of transplantation, as well as an important cause of acute kidney injury in clinical practice. Pre- and post-ischemic conditioning are strategies that may ...
Exercise induces early and late myocardial preconditioning in dogs
(2002)
Objective: We tested the hypothesis that exercise induces myocardial preconditioning in dogs. Methods: We instrumented dogs with a snare on the anterior descending coronary artery and catheters in the root of the aorta, ...
The role of ischemic preconditioning and pentoxifylline in intestinal ischemia/reperfusion injury of rats
(Acta Cirurgica Brasileira, 2017)
Purpose: To investigate the role of ischemic preconditioning (IPC) and pentoxifylline (PTX) in intestinal mucosa ischemia/reperfusion injury (IR). Methods: Thirty rats were assigned to 5 groups (N= 6): (CG): no clamping ...
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart
(ELSEVIER, 2012-04)
Pharmacological preconditioning limits myocardial infarct size after ischemia/reperfusion. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist used in anesthesia that may have cardioprotective properties against ...
Global and Ocular Hypothermic Preconditioning Protect the Rat Retina from Ischemic Damage
(Public Library Science, 2013-04)
Retinal ischemia could provoke blindness. At present, there is no effective treatment against retinal ischemic damage.
Strong evidence supports that glutamate is implicated in retinal ischemic damage. We investigated ...
Effects of wortmannin on cardioprotection exerted by ischemic preconditioning in rat hearts subjected to ischemia-reperfusion
(Servicio Publicaciones Universidad Navarra, 2016-03)
Ischemic preconditioning (IPC) is one of the most powerful interventions to reduce ischemia-reperfusion injury. The aim of the present study was to investigate the involvement of the phosphatidylinositol-3-kinases (PI3Ks) ...
Heart injury following intestinal ischemia reperfusion in rats is attenuated by association of ischemic preconditioning and adenosine
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2014-01-01)
PURPOSE: To investigate the effect of ischemic preconditioning (IPC) and adenosine as strategies to protect cardiac injury caused by intestinal IR in rats, based on increasing in adenosine bioavailability and improvement ...