Buscar
Mostrando ítems 1-4 de 4
Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB1R) “Cis-On” Agonist
(American Chemical SocietyEstados Unidos America, 2022-07-26)
Activation of the human cannabinoid receptor type 1 (hCB1R) with high spatiotemporal control is useful to study processes involved in different pathologies related to nociception, metabolic alterations, and neurological ...
Lipid-independent control of endothelial and neuronal TRPC3 channels by light
(Royal Society of Chemistry, 2019-01)
Lipid-gated TRPC channels are highly expressed in cardiovascular and neuronal tissues. Exerting precise pharmacological control over their activity in native cells is expected to serve as a basis for the development of ...
Lipid-independent control of endothelial and neuronal TRPC3 channels by light
(Royal Society of Chemistry, 2019)
Abstract: Lipid-gated TRPC channels are highly expressed in cardiovascular and neuronal tissues. Exerting precise pharmacological control over their activity in native cells is expected to serve as a basis for the development ...
New photochromic azoderivatives with potent acetylcholinesterase inhibition
(Elsevier Science SA, 2021-09-01)
The design of photochromic cholinesterase inhibitors is a challenge of the photopharmacological approach towards the remote control of acetylcholinesterase (AChE) enzyme and its potential application in Alzheimer's disease ...