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A review of pharmacokinetic parameters of metabolites and prodrugs
(Drug Metabolism Letters, 2014)
In drug discovery and development, the kinetic study of active metabolites plays an important role, helping to define the time course of the drug in the body and its activity or toxicity. After a pharmacokinetics assessment ...
A review of pharmacokinetic parameters of metabolites and prodrugs
(2013-01-01)
In drug discovery and development, the kinetic study of active metabolites plays an important role, helping to define the time course of the drug in the body and its activity or toxicity. After a pharmacokinetics assessment ...
Reply to "Adequate design of pharmacokinetic-pharmacodynamic studies will help optimize tuberculosis treatment for the future"
(American Society for Microbiology, 2015)
We thank Sturkenboom et al. for their interest in our study and their comments. The pragmatic study design based on two sampling points, 2 and 6 h after drug intake, reflected the real-world approach taken in this study, ...
A review of pharmacokinetic parameters of metabolites and prodrugs
(Drug Metabolism Letters, 2015)
A review of pharmacokinetic parameters of metabolites and prodrugs
(Drug Metabolism Letters, 2015)
Pharmacokinetics of whole IgG equine antivenom: comparison between normal and envenomed rabbits
(2006-09-01)
Pharmacokinetics of antivenoms has been mainly studied in normal animals, whereas very little is known on pharmacokinetics in envenomed animals. The aim of this study was to compare pharmacokinetic parameters of whole IgG ...
Pharmacokinetics of whole IgG equine antivenom: comparison between normal and envenomed rabbits
(2006-09-01)
Pharmacokinetics of antivenoms has been mainly studied in normal animals, whereas very little is known on pharmacokinetics in envenomed animals. The aim of this study was to compare pharmacokinetic parameters of whole IgG ...
Pharmacokinetics of lysine clonixinate in children in postoperative care
(DUSTRI-VERLAG DR KARL FEISTLE, 1996)
The pharmacokinetics of 2 doses of intravenous lysine clonixinate (4 and 6 mg x kg(-1)) were studied in 10 children (age 4 - 10 years) under postoperative care, A single dose of the drug was injected in a forearm vein, ...