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A novel peptidoglycan D,L-endopeptidase induced by Salmonella inside eukaryotic cells contributes to virulence
(Wiley Blackwell Publishing, Inc, 2016-02)
Bacteria remodel peptidoglycan structure in response to environmental changes. Many enzymes are involved in peptidoglycan metabolism; however, little is known about their responsiveness in a defined environment or the modes ...
Protected N-Acetyl Muramic Acid Probes Improve Bacterial Peptidoglycan Incorporation via Metabolic Labeling
(American Chemical Society, 2021-09)
Metabolic glycan probes have emerged as an excellent tool to investigate vital questions in biology. Recently, methodology to incorporate metabolic bacterial glycan probes into the cell wall of a variety of bacterial species ...
Localizing Peptidoglycan Synthesis in Helicobacter pylori using Clickable Metabolic Probes
(John Wiley & Sons Inc., 2021-04)
The bacterial cell wall, composed of peptidoglycan (PG), provides structural integrity for the cell and is responsible for cell shape in most bacteria. Here we present tools to study the cell wall using a clickable PG-specific ...
Transposons and pathogenicity in Xanthomonas: acquisition of murein lytic transglycosylases by TnXax1 enhances Xanthomonas citri subsp. citri 306 virulence and fitness
(Peerj Inc, 2018-12-19)
Xanthomonas citri subsp. citri 306 (XccA) is the causal agent of type A citrus canker (CC), one of the most significant citriculture diseases. Murein lytic transglycosylases (LT), potentially involved in XccA pathogenicity, ...
Different Vancomycin-Intermediate Staphylococcus aureus Phenotypes Selected from the Same ST100-hVISA Parental Strain
(Mary Ann Liebert, 2017-01)
The aim of this study is to characterize the factors related to peptidoglycan metabolism in isogenic hVISA/VISA ST100 strains. Recently, we reported the increase in IS256 transposition in invasive hVISA ST100 clinical ...
Proteomic Analysis of Rhizobium favelukesii LPU83 in Response to Acid Stress
(American Chemical Society, 2019-08-21)
Acid soils constitute a severe problem for leguminous crops mainly through a disturbance in rhizobium-legume interactions. Rhizobium favelukesii - an acid-tolerant rhizobium able to nodulate alfalfa - is highly competitive ...
Caracterização de transglicosilases líticas de mureína em xanthomonas citri subsp. citri 306 e estudo funcional das lts mltb2.1 e mltb2.2 associadas ao elemento Tnxax1
(Universidade Estadual Paulista (Unesp), 2018-07-04)
Xanthomonas citri subsp. citri 306 (XccA) é o agente causal do cancro cítrico (CC), doença endêmica que afeta a citricultura. Durante a interação patógeno-hospedeiro o sistema de secreção tipo três (SST3) codificado pela ...
c-di-GMP-related phenotypes are modulated by the interaction between a diguanylate cyclase and a polar hub protein
(NATURE PUBLISHING GROUP, 2020)
XAC4296: A multidomain and exclusive Xanthomonadaceae protein related to chromosome segregation, cell division, and bacterial fitness
(Universidade Estadual Paulista (Unesp), 2022-05-13)
Os micro-organismos apresentam um repertório limitado e extremamente adaptável de genes. Muitos destes genes codificam para proteínas contendo um único domínio ou multidomínios proteicos variáveis, sendo que em ambos os ...