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Bulevirtide in the Treatment of Hepatitis Delta: Drug Discovery, Clinical Development and Place in Therapy
It has been ten years since the identification of NTCP as the cell surface receptor for HBV and HDV entry into hepatocytes. The search for molecules interfering with the binding of NTCP and HBV/HDV led to design bulevirtide ...
Efficacy and safety of peginterferon lambda for Covid-19, indications of a new antiviralEficacia y seguridad del peginterferón lambda para la Covid-19, indicios de un nuevo antiviral
(Boletín de Malariología y Salud Ambiental, 2021)
Introduction: Interferons are a family of cytokines that act on the innate immune response of the respiratory epithelium, a site of widespread viral invasion such as SARS-CoV-2. Objective: to analyze the published medical ...
IL28B Polymorphisms Among Latin American HCV Patients
(2013)
Latin America is a diverse region with more than 500 million people and approximately 8 million HCV infected individuals. The recent description of genetic polymorphisms associated to the interleukin 28B gene that predicts ...
Evaluación de los antígenos virales como factores pronósticos de respuesta al tratamiento con interferón alfa en pacientes con Hepatitis B Crónica: Revisión sistemática y meta análisis
(Universidad Nacional de ColombiaBogotá - Medicina - Maestría en Epidemiología ClínicaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021)
El interferón alfa y los análogos de nucleótidos son los pilares del tratamiento para la Hepatitis B Crónica ; los análogos de nucleótidos son los más usados debido a una menor tasa de eventos adversos, en comparación al ...
Influência dos polimorfismos nos genes IFNL3 e IFNL4 na resposta virológica sustentada e na produção de citocinas em pacientes brasileiros com hepatite c crônica tratados com alfapeginterferona
(2018)
A hepatite C crônica (HCC) é um grande problema de Saúde Pública, pois se apresenta como uma doença assintomática, onde 20% irão progredir para cirrose, podendo ainda evoluir para carcinoma hepatocelular. Os polimorfismos ...