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Circulating forms of parathyroid hormone detected with an immunofluorometric assay in patients with primary hyperparathyroidism and in hyperparathyroidism secondary to chronic renal failure
(Associação Brasileira de Divulgação Científica, 2001-12-01)
In patients with uremia, intact parathyroid hormone (PTH) measurement appears to overestimate the biologically active hormone in circulation. The recent description of the accumulation in these patients of a non-intact PTH ...
Pro-apoptotic effects of parathyroid hormone in intestinal cells
(National Research Council Canada-NRC Research Press, 2009-03-20)
Apoptosis, a form of programmed cell death, is a process fundamental to normal growth and development, immune response, tissue remodeling after injury or insult, and homeostasis of the intestinal epithelium. Recently, it ...
Evolution of PTH assays
(Sociedade Brasileira de Endocrinologia e Metabologia, 2006-08-01)
PTH metabolism is complex and the circulating forms include the intact 1-84 molecule as well as several carboxyl-terminal fragments. The first generation of PTH assays included several types of competitive assays, with ...
Paratormônio e osteoporose: encontrando o fio da meada. Bases fisiológicas para utilização do PTH no tratamento da osteoporose
(Sociedade Brasileira de Endocrinologia e Metabologia, 2002-06-01)
Parathyroid hormone (PTH) will be available in a few months for the treatment of osteoporosis. When used as a single daily subcutaneous injection for at least 1 year, it increases bone mass and reduces fracture rate more ...
Estudo de metodologias para avaliação do hormônio da paratireóide humano recombinante
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2013-01-31)
Human parathyroid hormone (hPTH) is a polypeptide with 84 amino acids and it is the
most important peptide regulator for calcium and phosphate ion homeostasis, maintaining
bone structure. Recombinant human parathyroid ...
Heterogeneity of carboxyl-terminal parathyroid hormone circulating forms in patients with hyperparathyroidism due to end stage renal disease
(Sociedade Brasileira de Endocrinologia e Metabologia, 2009-12-01)
OBJECTIVE: To study carboxyl-terminal (COOH) parathyroid hormone (PTH) circulating forms in patients with hyperparathyroidism due to end stage renal disease (ESRD). METHODS: An immunometric assay that recognizes both intact ...
Increased vertebral morphometric fracture in patients with postsurgical hypoparathyroidism despite normal bone mineral density
(BioMed CentralLondon, 2013)
Background
In human malaria, the naturally-acquired immune response can result in either the elimination of the parasite or a persistent response mediated by cytokines that leads to immunopathology. The cytokines are ...
Avaliação da potência do hormônio da paratireóide humano recombinante por bioensaio, métodos cromatográficos e eletroforético
(Universidade Federal de Santa MariaBrasilAnálises Clínicas e ToxicológicasUFSMPrograma de Pós-Graduação em Ciências FarmacêuticasCentro de Ciências da Saúde, 2017-05-24)
The human parathyroid hormone (hPTH) is a polypeptide secreted by the parathyroid glands that is essential for the maintenance of the calcium ion homeostasis in the blood. The recombinant DNA technology has enabled the ...