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Parameters affecting cellular invasion and escape from the parasitophorous vacuole by different infective forms of Trypanosoma cruzi
(Instituto Oswaldo Cruz, Ministério da Saúde, 2003-10-01)
In this study we have examined certain aspects of the process of cell invasion and parasitophorous vacuole escape by metacyclic trypomastigotes and extracellular amastigote forms of Trypanosoma cruzi (G strain). Using Vero ...
Trypanosoma cruzi invasion in non-phagocytic cells: an ultrastructural study
(Instituto de Histología y Embriología "Dr. Mario Burgos", 2018-12)
Trypanosoma cruzi is the causative agent of Chagas disease. This parasite requires the intracellular niche in order to proliferate and disseminate the infection. After invasion, T. cruzi resides temporarily in an acidic ...
A century of research: what have we learned about the interaction of Trypanosoma cruzi with host cells?
(Instituto Oswaldo Cruz, Ministério da Saúde, 2009-07-01)
Since the discovery of Trypanosoma cruzi and the brilliant description of the then-referred to new tripanosomiasis by Carlos Chagas 100 years ago, a great deal of scientific effort and curiosity has been devoted to ...
A century of research: what have we learned about the interaction of Trypanosoma cruzi with host cells?
(Instituto Oswaldo Cruz, Ministério da Saúde, 2009)
Since the discovery of Trypanosoma cruzi and the brilliant description of the then-referred to "new tripanosomiasis" by Carlos Chagas 100 years ago, a great deal of scientific effort and curiosity has been devoted to ...
Mammalian cell invasion and intracellular trafficking by Trypanosoma cruzi infective forms
(Academia Brasileira de Ciências, 2005-03-01)
Trypanosoma cruzi, the etiological agent of Chagas disease, occurs as different strains or isolates that may be grouped in two major phylogenetic lineages: T. cruzi I, associated with the sylvatic cycle and T. cruzi II, ...
Acidification modulates the traffic of Trypanosoma cruzi trypomastigotes in Vero cells harbouring Coxiella burnetii vacuoles
(Elsevier B.V., 2003-02-01)
We studied the fate of different Trypanosoma cruzi trypomastigote forms after they invade Vero cells persistently colonised with Coxiella burnetii. When the invasion step was examined we found that persistent C. burnetii ...
Estudo do papel diferencial de cada uma das isoformas da proteína lisossomal LAMP (LAMP-1E LAMP-2) no processo de infecção celular pelo Trypanosoma cruzi
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Biologia CelularUFMG, 2014-02-28)
Trypanosoma cruzi, an obligatory intracellular parasite, is capable of triggering a series of signaling events in host cells, many of them leading to calcium mobilization from intracellular stocks. Increase in cytosolic ...
Recruitment of galectin-3 during cell invasion and intracellular trafficking of Trypanosoma cruzi extracellular amastigotes
(Oxford Univ Press Inc, 2014-02-01)
The invasion of host cells by the intracellular protozoan Trypanosoma cruzi requires interactions with host cell molecules, and the replication of the parasite requires escape from a parasitophorous vacuole into the host ...
Trypanosoma cruzi
(Cell Press, 2021)
Trypanosoma cruzi is the etiological agent of American trypanosomiasis, or Chagas disease, and is transmitted mainly by blood-sucking reduviid insects in endemic countries. Metacyclic trypomastigotes released in the feces ...
Trypanosoma cruzi cell invasion and traffic: Influence of Coxiella burnetii and pH in a comparative study between distinct infective forms
(Elsevier B.V., 2007-07-01)
Previous studies have shown that Coxiella burnetii, an intracellular bacterium that resides within acidified vacuoles with secondary lysosomal characteristics, is an effective modulator of the intracellular traffic of ...