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An acetylation site in lectin domain modulates the biological activity of polypeptide GalNAc-transferase-2
(De Gruyter, 2012-12)
Polypeptide GalNAc-transferases (ppGalNAc-Ts) are a family of enzymes that catalyze the initiation of mucintype O -glycosylation. All ppGalNAc-T family members contain a common (QXW) 3 motif, which is present in the R-type ...
C57BL/6 alpha-1,3-Galactosyltransferase Knockout Mouse as an Animal Model for Experimental Chagas Disease
(American Chemical Society, 2023)
Ligand Reduces Galectin-1 Sensitivity to Oxidative Inactivation by Enhancing Dimer Formation
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2009)
Galectin-1 (Gal-1) regulates leukocyte turnover by inducing the cell surface exposure of phosphatidylserine (PS), a ligand that targets cells for phagocytic removal, in the absence of apoptosis. Gal-1 monomer- dimer ...
Anticorpos IgG e IgM Anti-α-GAL (Galα1,3Galβ1,4GlcNAc-R) em pacientes infectados por Plasmodium vivax
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em ParasitologiaUFMG, 2018-08-30)
Plasmodium vivax is the most widely distributed plasmodium species in the world. In Brazil it is the main species associated with malaria infection. The recognition of occurrence of severe malaria cases in P. vivax infections ...
Neuronal death in Drosophila triggered by GAL4 accumulation
(Wiley, 2007-12)
The GAL4/UAS system has been extensively employed in Drosophila to control gene expression in defined spatial patterns. More recently this system has been successfully applied to express genes involved in neurodegeneration ...
Papel das Galectinas-1, -3 e -9 em doenças inflamatórias crônicas da pele.
(Universidade Estadual Paulista (Unesp), 2021-09-01)
As respostas imunes que envolvem as inflamações crônicas da pele, tais como psoríase e dermatite, são complexas e evidenciam o desafio no diagnóstico clínico, sendo fundamental o estudo de biomarcadores para melhor definição ...
Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion
(AMER ASSOC IMMUNOLOGISTS, 2008)
Galectin-1 (Gal-1) and galectin-3 (Gal-3) exhibit profound but unique immunomodulatory activities in animals but their molecular mechanisms are incompletely understood. Early studies suggested that Gal-1 inhibits leukocyte ...