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Fibroblast contributes for osteoblastic phenotype in a MAPK-ERK and sonic hedgehog signaling-independent manner
(2017-12-01)
We hypothesized that a crosstalk between osteoblast and fibroblast (FB) exists, which contributes to bone as a dynamic tissue. Cell-free supernatants were harvested from fibroblast cultures and later subject pre-osteoblasts ...
Proinflammatory response of human osteoblastic cell lines and Osteoblast-monocyte interaction upon infection with Brucella spp
(American Society for Microbiology, 2009-03)
The ability of Brucella spp. to infect human osteoblasts and the cytokine response of these cells to infection were investigated in vitro. Brucella abortus, B. suis, B. melitensis, and B. canis were able to infect the ...
Osteoblasts engulf apoptotic bodies during alveolar bone formation in the rat maxilla
(Wiley-Blackwell, 2005-09-01)
During bone formation, as in other tissues and organs, intense cellular proliferation and differentiation are usually observed. It has been described that programmed cell death, i.e., apoptosis, takes place in the control ...
Osteoblasts engulf apoptotic bodies during alveolar bone formation in the rat maxilla
(Wiley-Blackwell, 2005-09-01)
During bone formation, as in other tissues and organs, intense cellular proliferation and differentiation are usually observed. It has been described that programmed cell death, i.e., apoptosis, takes place in the control ...
Soluble factors produced by PC-3 prostate cells decrease collagen content and mineralisation rate in fetal rat osteoblasts in culture
(Stockton Press, 1996)
Approximately 70% of patients with prostate cancer develop bone metastases in the advanced state
of the disease. In the present study, we sought to test the hypothesis that prostatic cancer cells produce factors
that ...
Low-level laser therapy for osteonecrotic lesions: effects on osteoblasts treated with zoledronic acid
(Springer, 2014-10-01)
Clinical studies have shown that low-level laser therapy (LLLT) can improve local tissue healing of bisphosphonate-induced osteonecrosis of the jaw. However, the effects of laser irradiation on bisphosphonate-treated ...
Mll-COMPASS complexes mediate H3K4me3 enrichment and transcription of the osteoblast master gene Runx2/p57 in osteoblasts
(Wiley, 2019)
Expression of Runx2/p57 is a hallmark of the osteoblast-lineage identity. Although several regulators that control the expression of Runx2/p57 during osteoblast-lineage commitment have been identified, the epigenetic ...