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Perspectives for a new drug candidate for Chagas disease therapy
(Fiocruz/IOC, 2022)
UHPLC Quantitation Method and In vitro Studies of Two New Phthalimide Derivatives Planned to Treat Sickle Cell Disease
(Bentham Science Publ Ltd, 2017-01-01)
Background: Sickle cell disease is characterized by the occurrence of acute disability and progressive organ damage, and it is one of the most common and severe monogenic disorders around the world. Since hydroxycarbamide ...
Aspirin Hybrid Molecules with Improved Antiplatelet Properties Designed As New Drug Candidates to Prevent Atherothrombosis
(Amer Soc Hematology, 2011-11-18)
Aspirin Hybrid Molecules with Improved Antiplatelet Properties Designed As New Drug Candidates to Prevent Atherothrombosis
(Amer Soc Hematology, 2011-11-18)
Signal amplifcation by reversible exchange for COVID‐19 antiviral drug candidates
Several drug candidates have been proposed and tested as the latest clinical treatment for coronavirus
pneumonia (COVID-19). Chloroquine, hydroxychloroquine, ritonavir/lopinavir, and favipiravir are
under trials for the ...
Prediction of drug targets in human pathogens
(Universidade Federal de Minas GeraisUFMG, 2017-02-21)
The rapid emergence of resistant bacteria makes today's antibiotics more and more ineffective, consequently increasing the need for new pharmacological targets and novel classes of antibacterial drugs. The identification ...
Current approaches to drug discovery for chagas disease: Methodological advances
(2019-01-01)
Background: In recent years, there has been an improvement in the in vitro and in vivo methodology for the screening of anti-chagasic compounds. Millions of compounds can now have their activity evaluated (in large compound ...
The antidepressant drug paroxetine as a new lead candidate in schistosome drug discovery
(Royal Society of Chemistry, 2016)