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Modulation of P75NTR/PRONGEF as a therapeutic approach for degenerative retinopathies
(Royal Society of Chemistry, 2018)
This chapter describes the experimental validation of neurotrophins / neurotrophin receptors as therapeutic targets for the treatment of retinal neurodegenerative disorders. Neuropathies often have inflammatory or vascular ...
Effect of Mycobacterium leprae on neurotrophins expression in human Schwann cells and mouse sciatic nerves
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Involvement of Nitric Oxide, Neurotrophins and HPA Axis in Neurobehavioural Alterations Induced by Prenatal Stress
(Springer, 2015)
Several studies suggest that negative emotions during pregnancy generate adverse effects on the cognitive, behavioural and emotional development of the descendants. The psychoneuroendocrine pathways involve the transplacentary ...
Neurotrophic control of ovarian development
(WILEY-LISS, DIV JOHN WILEY & SONS INC, 2002-12-15)
Substantial evidence now exists indicating that the neurotrophins, a family of growth factors required for the survival, development, and differentiation of various neuronal populations of the nervous system, are also ...
The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis
(BioMed Central, 2010-11)
The ability to regulate neurogenesis in the adult dentate gyrus will require further identification and characterization of the receptors regulating this process. In vitro and in vivo studies have demonstrated that ...
Generation and characterization of mice bearing null alleles of nradd/Nrh2
(Wiley-liss, Div John Wiley & Sons Inc, 2016-12)
The Neurotrophin receptor associated death domain gene (Nradd/Nrh2/Plaidd) is a type I transmembrane protein with a unique and short N-terminal extracellular domain and a transmembrane and intracellular domain that bears ...
Alteration of neurotrophin and cytokine expression in lymphocytes as novel peripheral markers of spatial memory deficits induced by prenatal stress
(Pergamon-Elsevier Science Ltd, 2017-05)
Much evidence has suggested that early life adversity can have a lasting effect on behavior. The aim of this study was to explore the impact of prenatal exposure to stress on cognition in adult life and how it impacts ...