Search
Now showing items 1-10 of 64
Na+, K+-ATPase response to neurotensin is altered by streptozotocin administration
(Research Trends, 2013-09)
Neurotensin is a basic tridecapeptide which can act as a neuromodulator or a neurotransmitter and binds to a group of receptors. Neurotensin is able to inhibit Na+, K+-ATPase activity, an effect blocked by the presence of ...
Neurotensin inhibits neuronal Na+, K+-ATPase activity through high affinity peptide receptor
(Elsevier Science Inc, 2000)
Mapping of neurotensin in the alpaca (Lama pacos) Brainstem
(Wiley, 2014)
We studied the distribution of cell bodies and fibres containing neurotensin (NT) in the brainstem of the alpaca using an indirect immunoperoxidase technique. Immunoreactive fibres were widely distributed throughout the ...
High affinity receptors but not low affinity receptors for neurotensin are involved in neuronal Na/K-ATPase inhibition by the peptide
(Research Trends, 2013-07)
Neurotensin acts as a neuromodulator or as a neurotransmitter that binds to a group of receptors. Two of the receptors, namely NTS1 and NTS2, bind to neurotensin with high affinity and low affinity, respectively. Neurotensin ...
Postnatal nitric oxide inhibition modifies neurotensin effect on ATPase activity
(Springer/Plenum Publishers, 2011-12)
We have previously showed that peptide neurotensin inhibits neuronal Na+, K+-ATPase activity, an effect which involves high affinity neurotensin receptor. Nitric oxide (NO) acts as a neurotransmitter or as a neuromodulator ...
Kinectics of Na+, K+-ATPase inhibition by calcitonin and neurotensin
(Research Trends, 2014-01)
The kinetics of interactions between the peptides calcitonin or neurotensin, and synaptosomal membrane Na+, K+-ATPase activity was characterized in this study. Calcitonin is a 32-amino acid peptide produced by the thyroid ...
Expression of neurotensin and its receptors in pituitary adenomas
(WILEY-BLACKWELL, 2008)
The neurotensin (NT) produced in the hypothalamus and in pituitary gonadotrophs and thyrotrophs participates in neuroendocrine regulation. Recently, the involvement of this peptide in normal and neoplastic cell proliferation ...
Neurotensin inhibitory effect on [ 3h]-ouabain binding to striatal membranes is inverted by administration of clozapine
(Nova Science Publishers, 2021)
Previous work indicates that peptide neurotensin inhibits synaptosomal membrane Na+, K+-ATPase activity. Anatomical and biochemical evidences indicate a relationship between neurotensinergic and dopaminergic systems and ...
Changes in [3H]-ouabain and [3H]-neurotensin binding to rat cerebral cortex membranes after administration of antipsychotic drugs haloperidol and clozapine
(Elsevier Science Inc, 2017-03)
Evidences indicate the relationship between neurotensinergic and dopaminergic systems. Neurotensin inhibits synaptosomal membrane Na+, K+-ATPase activity, an effect blocked by SR 48692, antagonist for high affinity neurotensin ...
The low affinity neurotensin receptor antagonist levocabastine impairs brain nitric oxide synthesis and mitochondrial function by independent mechanisms
(Wiley Blackwell Publishing, Inc, 2017-12)
Neurotensin is known to inhibit neuronal Na+, K+‐ATPase, an effect that is rescued by nitric oxide (NO) synthase inhibition. However, whether the neurotensinergic and the nitrergic systems are independent pathways, or are ...