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A New Approach to the Prediction of Partition Coefficients in Water/Organic Interfaces
(AMER SCIENTIFIC PUBLISHERS, 2009)
In the present work, a new approach for the determination of the partition coefficient in different interfaces based on the density function theory is proposed. Our results for log P(ow) considering a n-octanol/water ...
Effect of pH and dye concentration on the n-octanol/water distribution ratio of phenothiazine dyes: a microelectrode voltammetry study
(Elsevier B.V., 2014-10-20)
Microelectrode voltammetry was employed to gain information on the n-octanol/water partition ratio of phenothiazine dyes. the data were obtained as a function of pH and dye concentration in aqueous solutions. All the dyes ...
A 2D-QSPR approach to predict blood-brain barrier penetration of drugs acting on the central nervous system
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2010)
Drugs acting on the central nervous system (CNS) have to cross the blood-brain barrier (BBB) in order to perform their pharmacological actions. Passive BBB diffusion can be partially expressed by the blood/brain partition ...
Understanding the role of the hydrogen bond donor of the deep eutectic solvents in the formation of the aqueous biphasic systems
(2020-01-01)
Deep eutectic solvents (DES) have been proposed as phase-forming compounds of aqueous biphasic systems (ABS). However, due to DES nature and the high water content of the ABS, their nature and behavior remains controversial. ...
A new insight about pharmaceutical dosage forms for benzathine penicillin G
(2006-12-01)
In this work, a micellar system of benzathine penicillin G (BPG) in sodium deoxycholate (NaDC) was developed and evaluated physicochemically. The solubility profile of the drug in water and buffer solutions at various pH ...
A new insight about pharmaceutical dosage forms for benzathine penicillin G
(2006-12-01)
In this work, a micellar system of benzathine penicillin G (BPG) in sodium deoxycholate (NaDC) was developed and evaluated physicochemically. The solubility profile of the drug in water and buffer solutions at various pH ...
Distribution of urocanic acid isomers between aqueous solutions and n-octanol, liposomes or bovine serum albumin
(ELSEVIER, 2008-01-30)
The distribution of urocanic acid (UCA) isomers between aqueous solutions and n-octanol, egg yolk phosphatidylcholine (eggPC) liposomes or bovine serum albumin (BSA) has been evaluated. Regarding its partitioning between ...
QSPR models of boiling point, octanol-water partition coefficient and retention time index of polycyclic aromatic hydrocarbons
(Elsevier Science BvAmsterdamHolanda, 2003)