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Challenges of Translational Science
(Arquivos Brasileiros Cardiologia, 2017-05-01)
Euterpe oleracea mart. (açaí) reduces oxidative stress and improves energetic metabolism in myocardial ischemia-reperfusion injury in ratsEuterpe Oleracea Mart. (Açaí) reduz o estresse oxidativo e melhora o metabolismo energético da lesão de isquemia-reperfusão miocárdica em ratos
(2020-01-01)
Background: Euterpe oleracea Mart. (açaí) is a fruit with high antioxidant capacity and could be an adjuvant strategy to attenuate ischemia-reperfusion injury. Objective: To evaluate the influence of açaí in global ...
Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion
(2010)
Calpains contribute to reperfusion-induced myocardial cell death. However, it remains controversial whether its activation occurs during ischemia or reperfusion. We investigated the regulation and time-course of calpain ...
Cellular mechanisms against ischemia reperfusion injury induced by the use of anesthetic pharmacological agents
(Elsevier, 2014)
Ischemia–reperfusion (IR) cycle in the myocardium is associated with activation of an injurious cascade,
thus leading to new myocardial challenges, which account for up to 50% of infarct size. Some evidence
implicates ...
Erythropoietin protects the systolic function of neonatal hearts against ischaemia/reperfusion injury
(Oxford Univ Press IncCaryEUA, 2013)
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart
(ELSEVIER, 2012-04)
Pharmacological preconditioning limits myocardial infarct size after ischemia/reperfusion. Dexmedetomidine is an alpha(2)-adrenergic receptor agonist used in anesthesia that may have cardioprotective properties against ...
Endothelium-dependent coronary flow in ischemia reperfusion
(Gustav Fischer VerlagJenaAlemanha, 1997)
Signaling Pathways Involved in Myocardial Ischemia–Reperfusion Injury and Cardioprotection: A Systematic Review of Transcriptomic Studies in Sus scrofa
(MDPI. International Journal of Environmental Research and Public Health, 2023)
High cholesterol diet effects on ischemia- reperfusion injury of the heart
(National Research Council Canada-NRC Research Press, 2012-09)
Ischemic heart disease is the leading cause of morbi-mortality in developed countries. Both ischemia-reperfusion injury and mechanisms of cardioprotection have been studied for more than 50 years. It is known that the ...
Potential Therapies to Protect the Aging Heart Against Ischemia/Reperfusion Injury
(Frontiers Media, 2021)
Despite important advances in the treatment of myocardial infarction that have significantly reduced mortality, there is still an unmet need to limit the infarct size after reperfusion injury in order to prevent the onset ...