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Control of mast cell regulated exocytosis by Munc18 proteins
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2020-06-15)
Mast cells (MCs) play pivotal roles in many inflammatory conditions including allergic diseases. MCs store immunoregulatory compounds in their large cytoplasmic granules and, upon stimulation, secrete them via regulated ...
Platelets contribute to hemostasis, thrombosis, and allergic airway inflammation via Munc13-4-dependent secretion
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2018-11-01)
With over 200 million affected individuals, asthma is the most common chronic respiratory disease in the world. One old observation that begs an explanation is the relationship between platelets, their activation, and the ...
Protein expression of PKCZ (Protein Kinase C Zeta), Munc18c, and Syntaxin-4 in the insulin pathway in endometria of patients with polycystic ovary syndrome (PCOS)
(2012)
Background: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder commonly associated with
insulin resistance (IR). Previous studies indicate about the expression of molecules involved in the insulin pathway
in ...
Prolactin modulates the association and phosphorylation of SNARE and kinesin/MAP-2 proteins in neonatal pancreatic rat islets
(Elsevier Ireland LtdClareIrlanda, 2007)
Proteínas de exocitose do GLUT4 e suas interações em resposta à insulina nos tecidos muscular esquelético e adiposo de animais submetidos à desnutrição proteica na vida intrauterina e recuperados
(Universidade Federal de Mato GrossoBrasilFaculdade de Nutrição (FANUT)UFMT CUC - CuiabáPrograma de Pós-Graduação em Nutrição, Alimentos e Metabolismo, 2013-10-31)
Introduction: Changes in maternal nutrition during critical periods of fetal development and
lactation can lead to alterations in the offspring insulin sensitivity. Glucose uptake by GLUT4
in muscle and white adipose ...
Syntaxin 11 regulates platelet granule release and hemostasis
Degranulation, a form of regulated exocytosis, is essential for platelet participation in hemostasis.
The interaction between Syntaxin (Stx) and Munc18 proteins is required for exocytosis. We have
proven that selective ...