We discuss the estimation of the expected value of the quality-adjusted survival, based on multistate models. We generalize an earlier work, considering the sojourn times in health states are not identically distributed, ...

In clinical trials, it may be of interest taking into account physical and emotional well-being in addition to survival when comparing treatments. Quality-adjusted survival time has the advantage of incorporating information ...

In this paper, we consider a memristive circuit consisting of three elements: A passive linear inductor, a passive linear capacitor and an active memristive device. The circuit is described by a four-parameter system of ...

Often intermediate events provide more detailed information about the disease process or recovery, for example, and allow greater accuracy in predicting the prognosis of patients. Such non-fatal events during the course ...

We report on the bifurcation analysis of an extended Hindmarsh-Rose (eHR) neuronal oscillator. We prove that Hopf bifurcation occurs in this system, when an appropriate chosen bifurcation parameter varies and reaches its ...

In this work we study the interaction between two or three nonlinear dynamical macroeconomic idealized systems. The model is a modified version of the Bouali's system. Only three economic variables were considered: foreign ...

Regression models for the mean quality-adjusted survival time are specified from hazard functions of transitions between two states and the mean quality-adjusted survival time may be a complex function of covariates. We ...

We propose a multistate joint model to analyze interval-censored event-history data subject to within-unit clustering and nonignorable missing data. The model is motivated by a study of the neurocysticercosis (NC) cyst ...

This paper discusses the application of a multi-state model to diabetic retinopathy under the assumption that a continuous time Markov process determines the transition times between disease stages. The multi-state model ...