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Fungicidal activity of human monocyte-derived multinucleated giant cells induced in vitro by Paracoccidioides brasiliensis antigen
Multinucleated giant cells (MGC) are characteristic cells in granulomatous disorders such as paracoccidioidomycosis (PCM) and also are formed in vitro from peripheral blood mononuclear cells by several stimuli. In this ...
Granulocyte macrophage colony-stimulating factor enhances the modulatory effect of cytokines on monocyte-derived multinucleated giant cell formation and fungicidal activity against Paracoccidioides brasiliensis
(Instituto Oswaldo Cruz, Ministério da Saúde, 2011-09-01)
Multinucleated giant cells (MGC) are cells present in characteristic granulomatous inflammation induced by intracellular infectious agents or foreign materials. The present study evaluated the modulatory effect of granulocyte ...
Ultrastructural characteristics of connective tissue around porous hydroxyapatite hypodermic implants in rats
Adult Sprague-Dawley rats were implanted with porous hydroxyapatite (Interpore 200®), following a procedure different from that of Kawaguchi et al. Instead of implanting hydroxyapatite (Ha) in periodontal osseus defects, ...
Central Giant Cell Granuloma in Pediatric Maxilla: Surgical Management
(Lippincott Williams & Wilkins, 2014-07-01)
Central giant cell granuloma (CGCG) is an intraosseous lesion consisting of fibrous cellular tissue that contains multiple foci of hemorrhage, multinucleated giant cells, and occasional trabeculae of woven bone. An 8-year-old ...
Peripheral giant cell granuloma. An immunohistochemical and ultrastructural study.
OBJECTIVE: To study the nature of multinucleated and mononuclear cells from peripheral giant cell granuloma (PGCG). MATERIALS AND METHODS: Formalin-fixed, paraffin-embedded sections of 40 cases of PGCG were immunohistochemically ...