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Comparison of the Effects of Monastrol and Oxomonastrol on Human Hepatoma Cell Line HepG2/C3A
(Int Inst Anticancer Research, 2017-03-01)
Monastrol and its analog oxomonastrol differ by replacement of the sulfur atom present in monastrol to an oxygen atom in oxomonastrol. Monastrol inhibits the mitotic kinesin family member 11 (EG5), which has been studied ...
Antiproliferative activity of monastrol in human adenocarcinoma (MCF-7) and non-tumor (HB4a) breast cells
(Springer, 2016-12-01)
Monastrol is an allosteric inhibitor of the mitotic kinesin Eg5 that exhibits an antiproliferative effect against several cell lines. We investigated the antiproliferative effect of monastrol on human breast adenocarcinoma ...
Híbrido de monastrol-H2S : síntese e atividade antiproliferativa contra células de câncer de ovário
(Universidade Federal de Minas GeraisUFMG, 2015-08-07)
Cancer represents one of the mayor causes of death in the world. According to OMS, this illness has been responsible for 8,2 million deaths in 2012, mainly due to the absence of efficient methods and drugs for treatment. ...
Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)
Transition Metal-doped Heteropolyacid Catalysts for the Suitable Multicomponent Synthesis of Monastrol and Bioactive Related Compounds
(Bentham Science Publishers, 2018-02)
Background: Molybdophosphoric acid (PMo) is used in heterogeneous catalysis. The incorporation of vanadium in the primary structure and a transition metal in the secondary structure of PMo improves the oxidative and acidity ...
Novos complexos fenantrolínicos de cobre e cobalto com ligantes derivados do monastrol: síntese, estudo espectroscópico e eletroquímico
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM QUÍMICA, 2022-02-04)
Cobalt and copper complexes stand out as promising systems in the treatment of cancer, both due to the low toxicity of these metals in the biological environment, as well as the magnetic and
electrochemical properties, ...