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The in vitro leishmanicidal activity of hexadecylphosphocholine (miltefosine) against four medically relevant leishmania species of Brasil

Teixeira, Eliane de Morais; Damasceno, Quesia Souza; Galuppo, Mariana Kolos; Romanha, Alvaro José; Rabello, Ana Lúcia Teles (Fundação Oswaldo Cruz, 2014)

Efficacy of Apigenin and Miltefosine Combination Therapy against Experimental Cutaneous Leishmaniasis

Emiliano, Yago S. S.; Amaral, Elmo E. Almeida (American Chemical Society, 2018)

Successful Treatment of Primary Amoebic Meningoencephalitis Using a Novel Therapeutic Regimen Including Miltefosine and Voriconazole

Autor desconocido (Springer, 2022)

The genus Naegleria consists of free-living amoebae widely distributed worldwide in soil and freshwater habitats. Primary amoebic meningoencephalitis (PAM) is an uncommon and most likely fatal disease. The incubation period ...

Interaction of miltefosine with intercellular membranes of stratum corneum and biomimetic lipid vesicles

Alonso, Lais; Mendanha, Sebastiao Antonio; Marquezin, Cassia Alessandra; Barioni, Marina Berardi; Ito, Amando Siuiti; Ulises Acuna, A.; Alonso, Antonio (ELSEVIER SCIENCE BVAMSTERDAM, 2012)

Miltefosine (MT) is an alkylphospholipid approved for breast cancer metastasis and visceral leishmaniasis treatments, although the respective action mechanisms at the molecular level remain poorly understood. In this work, ...

Development and characterization of miltefosine-loaded polymeric micelles for cancer treatment

Valenzuela Oses, Johanna K.; García, Mónica Cristina; Feitosa, Valker A.; Pachioni Vasconcelos, Juliana A.; Gomes-Filho, Sandro M.; Lourenço, Felipe R.; Cerize, Natalia N.P.; Bassères, Daniela S.; Rangel-Yagui, Carlota O. (Elsevier Science, 2017-12)

Miltefosine presents antineoplastic activity but high hemolytic potential. Its use in cancer has been limited to treating cutaneous metastasis of breast cancer. To decrease hemolytic potential, we developed a formulation ...

Evaluation of the ability of Miltefosine associated with topical GM-CSF in modulating the immune response of patients with cutaneous Leishmaniasis

Peixoto, Fábio de Carvalho; Nascimento, Maurício; Costa, Rúbia; Silva, Juliana; Renard, Gaby; Guimarães, Luiz Henrique; Penna, Gerson Oliveira; Barral-Netto, Manoel; Carvalho, Lucas P.; Machado, Paulo Roberto Lima; Carvalho, Edgar M. (Hindawi, 2020)

Increased Leishmania infantum resistance to miltefosine and amphotericin B after treatment of a dog with miltefosine and allopurinol

Gonçalves, Gustavo; Campos, Monique Paiva; Gonçalves, Alessandra Silva; Medeiros, Lia Carolina Soares; Figueiredo, Fabiano Borges (Parasites & Vectors, 2021)

In Vitro Susceptibility to Miltefosine of Leishmania infantum (syn. L. chagasi) Isolates from Different Geographical Areas in Brazil

Espada, Caroline Ricce; Levatti, Erica V. de Castro; Boité, Mariana Côrtes; Lamounier, Dorcas; Alvar, Jorge; Cupolillo, Elisa; Costa, Carlos Henrique Nery; Rodde, Joelle; Uliana, Silvia R. B. (MDPI, 2021)

Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake

Espada, Caroline Ricce; Magalhães, Rubens M; Cruz, Mario C; Machado, Paulo Roberto; Schriefer, Albert; Carvalho, Edgar Marcelino de; Hornillos, Valentín; Alves, João M.; Cruz, Angela Kaysel; Coelho, Adriano Cappellazzo; Uliana, Silvia Reni Bortolin (Elsevier, 2019)

Effect of Itraconazole-Ezetimibe-Miltefosine Ternary Therapy in Murine Visceral Leishmaniasis

Andrade Neto, Valter V.; Rebello, Karina M.; Pereira, Thais M.; Santos, Eduardo Caio Torres (American Society for Microbiology, 2021)

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