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In vitro anti-echinococcal and metabolic effects of metformin involve activation of AMP-activated protein kinase in larval stages of Echinococcus granulosus
(Public Library of Science, 2015-05)
Metformin (Met) is a biguanide anti-hyperglycemic agent, which also exerts antiproliferative effects on cancer cells. This drug inhibits the complex I of the mitochondrial electron transport chain inducing a fall in the ...
Improvement of the In Vitro Culture of Echinococcus Granulosus Metacestodes
(MedCrave, 2017-05)
This work introduces a novel modification to the in vitro experimental vesiculardevelopment of the parasite. Our findings showed that protoscoleces exposed toinsulin developed into microcysts in shorter times. Moreover, a ...
Nefropatía asociada a VIH. reporte de un caso
(Universidad Peruana Cayetano Heredia. Facultad de Medicina "Alberto Hurtado", 2004)
Biochemical and molecular characterization of the calcineurin in Echinococcus granulosus larval stages
(Elsevier Science, 2015-06)
Calcineurin (CaN) is a Ca2+-calmodulin activated serine-threonine protein phosphatase that couples the local or global calcium signals, thus controlling important cellular functions in physiological and developmental ...
In vitro and in vivo effects of flubendazole on Echinococcus granulosus metacestodes
(Springer, 2006-12)
The aim of the present work was to determine the efficacy of flubendazole (FLBZ) against E. granulosus metacestodes by using in vitro and in vivo models. Groups of 50 microcysts developed in vitro and groups of 10 peritoneal ...
Detecção e caracterização molecular de Sarcocystis spp. em tecidos de ovinos abatidas em frigoríficos no Sul do Brasil
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2018-02-07)
Sarcocystis spp. are intracellular protozoan parasites with an intermediate-definitive host life cycle and can infect a wide range of animals. There are some differences among the Sarcocystis species related to the life ...
Epigenetic regulation of metalloproteinases and their inhibitors in rotator cuff tears
(Public Library Science, 2017)
Rotator cuff tear is a common orthopedic condition. Metalloproteinases (MMP) and their inhibitors (TIMP) seem to play a role in the development of joint injuries and in the failure of tissue healing. However, the mechanisms ...
Resultado postnatal de fetos con malformación adenomatoide quística pulmonar en la unidad maternofetal Clínica Colombia
(Universidad del RosarioEspecialización en Medicina Materno-FetalFacultad de Medicina, 2013)
Introduction Pulmonary Cystic Adenomatoid Malformation is a condition that develops during early stages of embryonic development and the prognosis depends on the size of the lung lesion. There are very few studies that ...
Lente de contato biossintética com liberação gradual de ofloxacina para tratamento de ceratite experimental por Staphylococcus aureus em cães
(Universidade Estadual Paulista (Unesp), 2008-02-28)
O contato da córnea com o meio externo torna-a a estrutura ocular mais passível de traumas e lesões, que podem acarretar em formação de intensa cicatriz ou até de perfuração, prejudicando a visão do animal. A utilização ...