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Computational Detection of MicroRNA Targets
(2022-01-01)
MicroRNAs (miRNAs) are small noncoding RNAs that are recognized as posttranscriptional regulators of gene expression. These molecules have been shown to play important roles in several cellular processes. MiRNAs act on ...
miRTil: An Extensive Repository for Nile Tilapia microRNA Next Generation Sequencing Data
(2020-07-22)
Nile tilapia is the third most cultivated fish worldwide and a novel model species for evolutionary studies. Aiming to improve productivity and contribute to the selection of traits of economic impact, biotechnological ...
Combining results from distinct microRNA target prediction tools enhances the performance of analyses
(2017-05-09)
Target prediction is generally the first step toward recognition of bona fide microRNA (miRNA)-target interactions in living cells. Several target prediction tools are now available, which use distinct criteria and stringency ...
comTAR: a web tool for the prediction and characterization of conserved microRNA targets in plants
(Oxford University Press, 2014-01)
Motivation: MicroRNAs (miRNAs) are major regulators of gene expression in plants and animals. They recognize their target messenger RNAs (mRNAs) by sequence complementarity and guide them to cleavage or translational arrest. ...
Competing endogenous RNA networks in the epithelial to mesenchymal transition in diffuse-type of gastric cancer
(MDPI, 2020)
The diffuse-type of gastric cancer is associated with epithelial to mesenchymal transition. Loss of E-cadherin expression is the hallmark of this process and is largely due to the upregulation of the transcription factors ...
Single nucleotide polymorphisms affect miRNA target prediction in bovine
(2021-04-01)
Single nucleotide polymorphisms (SNPs) can have significant effects on phenotypic characteristics in cattle. MicroRNAs (miRNAs) are small, non-coding RNAs that act as post-transcriptional regulators by binding them to ...
CeRNAs in plants: Computational approaches and associated challenges for target mimic research
(2017-05-30)
The competing endogenous RNA hypothesis has gained increasing attention as a potential global regulatory mechanism of microRNAs (miRNAs), and as a powerful tool to predict the function of many noncoding RNAs, including ...
Identification of MicroRNA-like molecules derived from the antigenome RNA of hepatitis C virus: a bioinformatics approach
(Scientific Research Publishing, 2016)
MicroRNAs (miRNAs) are small, noncoding RNA molecules that play important roles in the regula-tion of gene expression of the cell. Recent studies have described cytoplasmic RNA virus genome-derived miRNAs. Moreover, miRNAs ...
Genome-wide identification of microRNA targets in the neglected disease pathogens of the genus Echinococcus
(Elsevier Science, 2017-04)
MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at post-transcriptional level and play essential roles in biological processes such as development. MiRNAs silence target mRNAs ...
Genome-wide identification of microRNA targets in the neglected disease pathogens of the genus Echinococcus
(2017-06)
MicroRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at posttranscriptional level and play essential roles in biological processes such as development. MiRNAs silence target mRNAs by ...