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Circulating microRNAs in Huntington's disease: Emerging mediators in metabolic impairment
(Academic Press, 2016)
Avaliação funcional do hsa-miR-22-3p em células endoteliais como possível alvo antiangiogênico no câncer de próstata
(Florianópolis, SC, 2021-09-22)
O câncer de próstata é o tipo de câncer mais comum entre a população masculina. Segundo dados do INCA, ele corresponde a 29% dos diagnósticos de câncer no país. É o segundo tipo de câncer responsável pela mortalidade entre ...
Integrative miRNA and mRNA analysis in penile carcinomas reveals markers and pathways with potential clinical impact
(2017-01-01)
Penile carcinoma (PeCa) is an important public health issue in poor and developing countries, and has only recently been explored in terms of genetic and epigenetic studies. Integrative data analysis is a powerful method ...
Combining results from distinct microRNA target prediction tools enhances the performance of analyses
(2017-05-09)
Target prediction is generally the first step toward recognition of bona fide microRNA (miRNA)-target interactions in living cells. Several target prediction tools are now available, which use distinct criteria and stringency ...
Intrahippocampal Inoculation of Aβ1–42 Peptide in Rat as a Model of Alzheimer’s Disease Identified MicroRNA-146a-5p as Blood Marker with Anti-Inflammatory Function in Astrocyte Cells
(MDPI, 2023)
Circulating microRNAs (miRNAs) have aroused a lot of interest as reliable blood diagnostic biomarkers of Alzheimer's disease (AD). Here, we investigated the panel of expressed blood miRNAs in response to aggregated ...
Down-regulation of SLC8A1 as a putative apoptosis evasion mechanism by modulation of calcium levels in penile carcinoma
(Elsevier B.V., 2015-07-01)
Purpose: The SLC8A1 gene, which encodes the Na+/Ca2(+) exchanger, has a key role in calcium homeostasis. Our previous gene expression oligoarray data revealed SLC8A1 under expression in penile carcinoma. We investigated ...
Altered microRNA expression levels in mononuclear cells of patients with pulmonary and pleural tuberculosis and their relation with components of the immune response
(Elsevier, 2012-09)
Different lines of evidence demonstrate that microRNAs (miRNAs) play an important role in host–pathogen interactions. In this study we investigated the expression patterns of several miRNAs, most of them involved in ...
Circulating microRNA expression profile in B-cell acute lymphoblastic leukemia
(IOS Press, 2015)
BACKGROUND: Acute lymphoblastic leukemia (ALL) is a highly diverse disease characterized by cytogenetic and molecularabnormalities, including altered microRNA (miRNA) expression signatures.
AIM: We perform and validate a ...