Buscar
Mostrando ítems 1-10 de 80
Plasma microRNAs as biomarkers for Lamin A/C-related dilated cardiomyopathy
(Springer Verlag, 2018)
Identification of MicroRNA-like molecules derived from the antigenome RNA of hepatitis C virus: a bioinformatics approach
(Scientific Research Publishing, 2016)
MicroRNAs (miRNAs) are small, noncoding RNA molecules that play important roles in the regula-tion of gene expression of the cell. Recent studies have described cytoplasmic RNA virus genome-derived miRNAs. Moreover, miRNAs ...
Evolutionary implications of the microRNA- and piRNA complement of Lepidodermella squamata (Gastrotricha)
(MDPI, 2019)
Gastrotrichs—’hairy bellies’—are microscopic free-living animals inhabiting marine and freshwater habitats. Based on morphological and early molecular analyses, gastrotrichs were placed close to nematodes, but recent ...
MicroRNA expression profile in head and neck cancer: HOX-cluster embedded microRNA-196a and microRNA-10b dysregulation implicated in cell proliferation
(2013-11-09)
Abstract
Background
Current evidence implicates aberrant microRNA expression patterns in human malignancies; measurement of microRNA expression may have diagnostic and prognostic ...
Intrahippocampal Inoculation of Aβ1–42 Peptide in Rat as a Model of Alzheimer’s Disease Identified MicroRNA-146a-5p as Blood Marker with Anti-Inflammatory Function in Astrocyte Cells
(MDPI, 2023)
Circulating microRNAs (miRNAs) have aroused a lot of interest as reliable blood diagnostic biomarkers of Alzheimer's disease (AD). Here, we investigated the panel of expressed blood miRNAs in response to aggregated ...
Identificação de alteração gênica em regiões de ligação de micrornas na disgenesia tireoidiana
(Universidade Federal de São Paulo, 2018)
O hipotireoidismo congênito (HC) é a síndrome endócrina pediátrica mais frequente cuja principal causa é a disgenesia tireoidiana (DT) decorrente de defeitos embriológicos da tireoide. A DT pode ser dividida em três ...
Genome-wide profiling and predicted significance of post-mortem brain microRNA in Alzheimer's disease
(Elsevier B.V., 2020-10-01)
Background: MicroRNAs (miRNAs) emerged as regulatory elements, with up to 70 % of all miRNAs found in the brain, playing key roles in the onset of Alzheimer's disease (AD). Objective: to broadly assess the expression levels ...
Artificial microRNAs as antiviral strategy to FMDV: structural implications of target selection
(2014-04)
RNA interference (RNAi) appears as a promising strategy to control virus replication. While the antiviral power of short-hairpin RNAs or small-interfering RNAs against FMDV has been demonstrated widely, safer RNAi effectors ...
Integrative transcriptome and microRNome analysis identifies dysregulated pathways in human Sertoli cells exposed to TCDD
(2018-11-01)
Male fertility and spermatogenesis are directly linked to the Sertoli cell's ability to produce factors associated with germ cell development. Sertoli cells express receptors for FSH and testosterone, and are the major ...